SCHEMBL1246404

SCHEMBL1246404

CCCC(F)c1cc(OC)ccc1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 3/20 0.46
TAS1R1 Q7RTX1 3/20 0.46
BCHE P06276 1/20 0.44
TYR P14679 1/20 0.44
ACHE P22303 1/20 0.44
GAA P10253 2/20 0.43
MAPT P10636 2/20 0.43
TDP2 O95551 1/20 0.43
POLB P06746 1/20 0.43
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
THRB P10828 1/20 0.42
RECQL P46063 1/20 0.42
BLM P54132 1/20 0.42
KMT2A Q03164 1/20 0.42
MCL1 Q07820 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ADRA2A P08913 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4596224 0.83 BCHE (0.50) TAS1R3TAS1R1BCHETYRACHE
SCHEMBL1246386 0.80 TYR (0.38) TYRMAPTMEN1ALDH1A1KMT2A
SCHEMBL3719984 0.79 GAA (0.50) BCHETYRACHEGAAMAPT
SCHEMBL1487568 0.78 HTR1A (0.35) TAS1R3TAS1R1ERN1
SCHEMBL1246437 0.78 LMNA (0.42) GAAMAPTMEN1ALDH1A1KMT2A
SCHEMBL1244546 0.77 TRPA1 (0.50) TAS1R3TAS1R1GAAMAPTPOLB
SCHEMBL13637390 0.76 RORC (0.54) BCHETYRACHEGAAMAPT
SCHEMBL30562928 0.76 RORC (0.54) BCHETYRACHEGAAMAPT
SCHEMBL1245729 0.75 GSR (0.42) GAAMAPTPOLBKDM4EMEN1
SCHEMBL16504443 0.75 ADRA2A (0.51) BCHETYRACHEGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2467424-A1 PHOTOVOLTAIC MODULE WITH STABILIZED POLYMERIC ENCAPSULANT BASF SE (DE) 2012-06-27 EP disclosed
EP-2300487-A1 HIGH PURITY MONOALKYLTIN COMPOUNDS AND USES THEREOF ARKEMA FRANCE (FR) 2011-03-30 EP disclosed
WO-2011020760-A1 PHOTOVOLTAIC MODULE WITH STABILIZED POLYMERIC ENCAPSULANT BASF SE (DE) 2011-02-24 WO disclosed
WO-2009138474-A1 HIGH PURITY MONOALKYLTIN COMPOUNDS AND USES THEREOF ARKEMA FRANCE (FR) 2009-11-19 WO disclosed