Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | PTPRF | P10586 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12464230 | 0.92 | KDM4E (0.44) | MAPTMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL12464388 | 0.88 | KDM4E (0.38) | MAPTMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL27592383 | 0.86 | ALDH1A1 (0.43) | MAPTMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL12372020 | 0.83 | KDM4E (0.40) | MAPTMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL14048991 | 0.83 | TRPM8 (0.46) | MAPTMEN1KMT2AIKBKBPTPRF | |
| SCHEMBL2158610 | 0.81 | KDM4E (0.40) | MAPTMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL2249001 | 0.81 | KDM4E (0.47) | MAPTMEN1KMT2AKDM4EIKBKB | |
| SCHEMBL2157591 | 0.80 | KDM4E (0.42) | MAPTKDM4EPTPRFPTPN1LMNA | |
| SCHEMBL12464523 | 0.79 | HSD17B1 (0.44) | MAPTMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL3812838 | 0.79 | KDM4E (0.39) | MAPTMEN1KMT2AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985769-B2 | Compounds and methods for the treatment or prevention of Flavivirus infections | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-07-26 | — | — | US | disclosed |