Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 10/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 10/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27669184 | 0.85 | HTR4 (0.37) | NPC1ALDH1A1MAPK1CARM1PRMT6 | |
| SCHEMBL14951795 | 0.82 | OPRM1 (0.35) | ALDH1A1MAPK1HRH3HSD11B1KCNH2 | |
| SCHEMBL4569265 | 0.78 | HRH3 (0.32) | ALDH1A1MAPK1HRH3HRH1KCNH2 | |
| SCHEMBL29297567 | 0.78 | HRH3 (0.32) | ALDH1A1MAPK1HRH3 | |
| SCHEMBL12632806 | 0.78 | KDM1A (0.35) | ALDH1A1MAPK1CARM1PRMT6HRH3 | |
| SCHEMBL13967070 | 0.78 | TLR9 (0.32) | ALDH1A1MAPK1HRH3HCRTR2TLR9 | |
| SCHEMBL21579256 | 0.78 | TLR9 (0.31) | HRH3TLR9TLR8TLR7 | |
| SCHEMBL22477411 | 0.77 | HRH3 (0.45) | NPC1CARM1PRMT6HRH3SIGMAR1 | |
| SCHEMBL16106672 | 0.77 | ALDH1A1 (0.36) | ALDH1A1MAPK1CARM1PRMT6SIGMAR1 | |
| SCHEMBL12820177 | 0.77 | DRD2 (0.34) | ALDH1A1MAPK1PRMT6SIGMAR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226113-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. | 2024-07-11 | — | — | US | disclosed |
| US-20110183938-A1 | 1,7-DIAZACARBAZOLES AND METHODS OF USE | GENENTECH, INC. (US) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240226113-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | TP53, HRAS, KRAS | NPC1 2050/4885ALDH1A1 2917/4885MAPK1 416/4885 |
| US-20110183938-A1 | 1,7-DIAZACARBAZOLES AND METHODS OF USE | CHEK1, CHEK2, BUB1B | NPC1 2505/4885ALDH1A1 576/4885MAPK1 359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.