SCHEMBL1246672

SCHEMBL1246672

O=C(c1ccccc1)N(CCO)C(=O)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 2/20 0.45
HDAC4 P56524 2/20 0.45
HDAC1 Q13547 2/20 0.45
HDAC2 Q92769 2/20 0.45
HDAC10 Q969S8 2/20 0.45
HDAC8 Q9BY41 2/20 0.45
HDAC6 Q9UBN7 2/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC11 Q96DB2 1/20 0.45
HDAC9 Q9UKV0 1/20 0.45
HDAC5 Q9UQL6 1/20 0.45
ADRA2C P18825 1/20 0.44
ALDH1A1 P00352 3/20 0.44
HPGD P15428 2/20 0.44
CES1 P23141 3/20 0.43
KMT2A Q03164 2/20 0.43
MAPK1 P28482 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17685267 0.89 ADRA2C (0.48) ADRA2CALDH1A1HPGDCES1KMT2A
SCHEMBL154607 0.83 HPGD (0.53) HDAC3HDAC4HDAC1HDAC2HDAC10
SCHEMBL16944257 0.82 ALDH1A1 (0.47) ADRA2CALDH1A1HPGDCES1KMT2A
SCHEMBL7203830 0.81 ALOX5 (0.47) HDAC3HDAC4HDAC1HDAC2HDAC10
Hydrochloric Acid SCHEMBL27871652 0.81 HPGD (0.52) HDAC3HDAC4HDAC1HDAC2HDAC10
SCHEMBL13571678 0.81 TP53 (0.52) HDAC1HDAC6ADRA2CALDH1A1HPGD
SCHEMBL633271 0.81 ADRA2C (0.56) HDAC1HDAC2ADRA2CALDH1A1HPGD
SCHEMBL3657378 0.79 ADRA2C (0.46) HDAC3HDAC4HDAC1HDAC2HDAC10
SCHEMBL1004454 0.79 KMT2A (0.51) HDAC4HDAC1HDAC6ALDH1A1HPGD
SCHEMBL5943718 0.79 ADRA2C (0.42) HDAC3HDAC4HDAC1HDAC2HDAC10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2394676-B1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITIATOR-CONTAINING SCAFFOLDS COLOPLAST AS (DK) 2018-03-28 EP disclosed
CN-103468108-B Coating composition COLOPLAST A/S (DK) 2016-03-02 CN disclosed
US-9169412-B2 Curable composition and image forming method FUJIFILM CORPORATION (JP) 2015-10-27 US disclosed
US-9169412-B2 Curable composition and image forming method FUJIFILM CORPORATION (JP) 2015-10-27 US disclosed
EP-2459242-B1 A MEDICAL DEVICE OF POLYOLEFIN COLOPLAST AS (DK) 2015-10-21 EP disclosed
EP-2104523-B1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST AS (DK) 2015-08-26 EP disclosed
US-20150210876-A1 CURABLE COMPOSITION AND IMAGE FORMING METHOD FUJIFILM CORPORATION (JP) 2015-07-30 US disclosed
US-20150210876-A1 CURABLE COMPOSITION AND IMAGE FORMING METHOD FUJIFILM CORPORATION (JP) 2015-07-30 US disclosed
US-8932662-B2 Coatings prepared from poly(ethylene oxide) and photo-initator-containing scaffolds COLOPLAST A/S (DK) 2015-01-13 US disclosed
EP-2459242-A2 A MEDICAL DEVICE OF POLYOLEFIN Coloplast A/S (DK) 2012-06-06 EP disclosed
US-20120121919-A1 MEDICAL DEVICE OF POLYOLEFIN COLOPLAST A/S (DK) 2012-05-17 US disclosed
WO-2011012137-A2 A MEDICAL DEVICE OF POLYOLEFIN COLOPLAST A/S (DK) 2011-02-03 WO disclosed
US-20100049146-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST A/S (DK) 2010-02-25 US disclosed
EP-2104523-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS Coloplast A/S (DK) 2009-09-30 EP disclosed
WO-2008071796-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST A/S (DK) 2008-06-19 WO disclosed