Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CASP6 | P55212 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 5/20 | 0.34 |
| ▸ | CA2 | P00918 | 5/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4145387 | 0.98 | ALDH1A1 (0.44) | ALDH1A1TDP1HPGDCASP6GAA | |
| SCHEMBL28859407 | 0.81 | CA2 (0.50) | ALDH1A1TDP1LMNACA1CA2 | |
| SCHEMBL4362006 | 0.81 | ALDH1A1 (0.38) | ALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL28524826 | 0.81 | VCAM1 (0.34) | ALDH1A1TDP1GAAHSD17B10CA1 | |
| SCHEMBL9320555 | 0.80 | KMT2A (0.32) | ALDH1A1TDP1HPGDGAACA1 | |
| SCHEMBL6759088 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HPGDGAALMNACA1 | |
| SCHEMBL9320310 | 0.77 | CA1 (0.53) | ALDH1A1GAAL3MBTL1LMNACA1 | |
| SCHEMBL9322097 | 0.76 | MMP2 (0.44) | ALDH1A1MMP2 | |
| SCHEMBL2041314 | 0.75 | ALDH1A1 (0.58) | ALDH1A1GAAL3MBTL1LMNATSHR | |
| SCHEMBL2041738 | 0.73 | VCAM1 (0.56) | ALDH1A1HPGDLMNATSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130295587-A1 | METHOD OF COUPLING BINDING AGENTS TO A SUBSTRATE SURFACE | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2013-11-07 | — | — | US | disclosed |
| WO-2012102663-A1 | METHOD OF COUPLING BINDING AGENTS TO A SUBSTRATE SURFACE | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2012-08-02 | — | — | WO | disclosed |