Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4145387 | 0.82 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL28524826 | 0.82 | VCAM1 (0.34) | ALDH1A1GAA | |
| SCHEMBL28859407 | 0.82 | CA2 (0.50) | ALDH1A1LMNAMAPT | |
| SCHEMBL6759088 | 0.81 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2PKMLMNAGAA | |
| SCHEMBL9320310 | 0.81 | CA1 (0.53) | ALDH1A1ALDH3A1SMN1; SMN2PKMLMNA | |
| SCHEMBL12466911 | 0.81 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL2041738 | 0.78 | VCAM1 (0.56) | ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL973134 | 0.77 | ALDH1A1 (0.43) | ALDH1A1PTGS2ALDH3A1ERN1ENPP2 | |
| SCHEMBL9320555 | 0.74 | KMT2A (0.32) | ALDH1A1GAAMAPT | |
| SCHEMBL9322097 | 0.74 | MMP2 (0.44) | ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113880762-B | Triacylamine derivatives containing 1,8-naphthalimide as well as preparation method and application thereof | 河北农业大学 | 2023-02-21 | — | — | CN | claimed |
| CN-113880762-A | 1, 8-naphthalimide-containing triacylamine derivatives, and preparation method and application thereof | 河北农业大学 | 2022-01-04 | — | — | CN | claimed |
| CN-103588685-B | Three ketones ammonium salt compound and preparation method thereof and application | Zhejiang Zhuji United Chemicals Co., Ltd. (CN) | 2016-01-13 | — | — | CN | claimed |
| CN-103588685-A | Triketone ammonium salt compounds and preparation method and application thereof | ZHEJIANG ZHUJI HELI CHEMICAL FOREIGN TRADE CO LTD | 2014-02-19 | — | — | CN | claimed |
| US-7029502-B2 | Azo dyes, a process for their preparation and their use in the production of colored plastics or polymeric color particles, and in the dyeing or printing of hydrophobic fiber materials | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-04-18 | — | — | US | claimed |
| US-6864253-B2 | Benzo[4,5]thieno[2,3-c]pyridine and Benzo[4,5]furo[2,3-c]pyridine Derivatives Useful as Inhibitors of Phosphodiesterase | ORTH-MCNEIL PHARMACEUTICAL, INC. (US) | 2005-03-08 | — | — | US | claimed |
| US-20040209776-A1 | Azole derivatives useful as insecticide | FAROOQ SALEEM | 2004-10-21 | — | — | US | claimed |
| CN-1533389-A | Azole derivatives useful as insecticide | — | 2004-09-29 | — | — | CN | claimed |
| EP-1414818-A1 | AZOLE DERIVATIVES USEFUL AS INSECTICIDE | Syngenta Limited (GB) | 2004-05-06 | — | — | EP | claimed |
| EP-1289985-B1 | BETA-CARBOLINE DERIVATIVES USEFUL AS INHIBITORS OF PHOSPHODIESTERASE | ORTHO MCNEIL PHARM INC (US) | 2003-12-10 | — | — | EP | claimed |
| US-20030166641-A1 | Beta-carboline derivatives useful as inhibitors of phosphodiesterase | SUI ZHIHUA (US) | 2003-09-04 | — | — | US | claimed |
| EP-0782632-B1 | A METHOD FOR IDENTIFYING AND USING COMPOUNDS THAT INACTIVATE HIV-1 AND OTHER RETROVIRUSES BY ATTACKING HIGHLY CONSERVED ZINC FINGERS IN THE VIRAL NUCLEOCAPSID PROTEIN | US GOV HEALTH & HUMAN SERV (US) | 2003-04-16 | — | — | EP | claimed |
| EP-1289985-A2 | BETA-CARBOLINE DERIVATIVES USEFUL AS INHIBITORS OF PHOSPHODIESTERASE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2003-03-12 | — | — | EP | claimed |
| WO-2003011861-A1 | AZOLE DERIVATIVES USEFUL AS INSECTICIDE | SYNGENTA LIMITED (GB) | 2003-02-13 | — | — | WO | claimed |
| US-6492358-B2 | FOR TREATMENT OF SEXUAL DISORDERS, MALE ERECTILE DYSFUNCTION | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2002-12-10 | — | — | US | claimed |
| US-6372752-B1 | ENZYME INHIBITORS, RESPIRATORY SYSTEM DISORDERS, TUBERCULOSIS AND MYCOBACTERIUM BACTERICIDES | GENZYME CORPORATION | 2002-04-16 | — | — | US | claimed |
| US-20020010189-A1 | beta-carboline derivatives useful as inhibitors of phosphodiesterase | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2002-01-24 | — | — | US | claimed |
| WO-2001087038-A2 | β-CARBOLINE DERIVATIVES USEFUL AS INHIBITORS OF PHOSPHODIESTERASE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-11-22 | — | — | WO | claimed |
| WO-2001056974-A2 | INHA INHIBITORS AND THEIR USE AS ANTIBACTERIALS | GENZYME CORPORATION (US) | 2001-08-09 | — | — | WO | claimed |
| CN-113880762-B | Triacylamine derivatives containing 1,8-naphthalimide as well as preparation method and application thereof | 河北农业大学 | 2023-02-21 | — | — | CN | disclosed |
| CN-110143932-B | Piperazinone derivatives, process for producing the same, inhibitor, and method for controlling root-parasitic weeds | 南开大学 | 2022-09-16 | — | — | CN | disclosed |
| CN-113880762-A | 1, 8-naphthalimide-containing triacylamine derivatives, and preparation method and application thereof | 河北农业大学 | 2022-01-04 | — | — | CN | disclosed |
| CN-111493078-A | Use of piperazinone derivatives, an accelerator and a method for controlling root parasitic weeds | 南开大学 | 2020-08-07 | — | — | CN | disclosed |
| WO-2019154284-A1 | PIPERAZINONE DERIVATIVE, PREPARATION METHOD THEREFOR, USE THEREOF, ACCELERATOR AND METHOD FOR CONTROLLING ROOT PARASITIC WEEDS | 南开大学 | 2019-08-15 | — | — | WO | disclosed |
| CN-106332895-A | Iodine oligosaccharide acid-containing synergistic weeding composition and applications thereof | 上海贯发海洋生物科技有限公司 | 2017-01-18 | — | — | CN | disclosed |
| CN-103588685-B | Three ketones ammonium salt compound and preparation method thereof and application | Zhejiang Zhuji United Chemicals Co., Ltd. (CN) | 2016-01-13 | — | — | CN | disclosed |
| CN-103588685-A | Triketone ammonium salt compounds and preparation method and application thereof | ZHEJIANG ZHUJI HELI CHEMICAL FOREIGN TRADE CO LTD | 2014-02-19 | — | — | CN | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| EP-1011729-B1 | OLIGONUCLEOTIDES WHICH SPECIFICALLY BIND RETROVIRAL NUCLEOCAPSID PROTEINS | US GOV HEALTH & HUMAN SERV (US) | 2008-01-09 | — | — | EP | disclosed |
| US-20070265231-A1 | Hydrazide Compounds for Combating Animal Pests | BASF AKTIENGESELLSCHAFT (DE) | 2007-11-15 | — | — | US | disclosed |
| EP-1819224-A1 | HYDRAZIDE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006125637-A1 | O-(PHENYL/HETEROCYCLYL)METHYL OXIME ETHER COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-30 | — | — | WO | disclosed |
| WO-2006058730-A1 | HYDRAZIDE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2006-06-08 | — | — | WO | disclosed |
| US-6943268-B2 | Method for induction of L-selectin shedding | SCIENCE & TECHNOLOGY CORPORATION @ UNM (US) | 2005-09-13 | — | — | US | disclosed |
| CN-1196699-C | Benzazoles: benzoxazole, benzthiazole and benzimidazole derivatives | ZENECA LTD (GB) | 2005-04-13 | — | — | CN | disclosed |
| US-6864253-B2 | Benzo[4,5]thieno[2,3-c]pyridine and Benzo[4,5]furo[2,3-c]pyridine Derivatives Useful as Inhibitors of Phosphodiesterase | ORTH-MCNEIL PHARMACEUTICAL, INC. (US) | 2005-03-08 | — | — | US | disclosed |
| US-20040209776-A1 | Azole derivatives useful as insecticide | FAROOQ SALEEM | 2004-10-21 | — | — | US | disclosed |
| CN-1533389-A | Azole derivatives useful as insecticide | — | 2004-09-29 | — | — | CN | disclosed |
| EP-1414818-A1 | AZOLE DERIVATIVES USEFUL AS INSECTICIDE | Syngenta Limited (GB) | 2004-05-06 | — | — | EP | disclosed |
| EP-1289985-B1 | BETA-CARBOLINE DERIVATIVES USEFUL AS INHIBITORS OF PHOSPHODIESTERASE | ORTHO MCNEIL PHARM INC (US) | 2003-12-10 | — | — | EP | disclosed |
| US-20030166641-A1 | Beta-carboline derivatives useful as inhibitors of phosphodiesterase | SUI ZHIHUA (US) | 2003-09-04 | — | — | US | disclosed |
| US-20030092763-A1 | Method for induction of L-selectin shedding | SCIENCE & TECHNOLOGY CORPORATION @UNM | 2003-05-15 | — | — | US | disclosed |
| US-6544989-B2 | Fungicidal, insecticidal, acaricidal, molluscicidal or nematicidal composition | SYNGENTA LIMITED (GB) | 2003-04-08 | — | — | US | disclosed |
| EP-1289985-A2 | BETA-CARBOLINE DERIVATIVES USEFUL AS INHIBITORS OF PHOSPHODIESTERASE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2003011861-A1 | AZOLE DERIVATIVES USEFUL AS INSECTICIDE | SYNGENTA LIMITED (GB) | 2003-02-13 | — | — | WO | disclosed |
| US-6492358-B2 | FOR TREATMENT OF SEXUAL DISORDERS, MALE ERECTILE DYSFUNCTION | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2002-12-10 | — | — | US | disclosed |
| EP-1100798-B1 | BENZAZOLE, BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES | SYNGENTA LTD (GB) | 2002-09-18 | — | — | EP | disclosed |
| US-6372752-B1 | ENZYME INHIBITORS, RESPIRATORY SYSTEM DISORDERS, TUBERCULOSIS AND MYCOBACTERIUM BACTERICIDES | GENZYME CORPORATION | 2002-04-16 | — | — | US | disclosed |
| US-20020010189-A1 | beta-carboline derivatives useful as inhibitors of phosphodiesterase | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2002-01-24 | — | — | US | disclosed |
| WO-2001087038-A2 | β-CARBOLINE DERIVATIVES USEFUL AS INHIBITORS OF PHOSPHODIESTERASE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-11-22 | — | — | WO | disclosed |
| CN-1320124-A | Benzazoles: benzoxazole, benzthiazole and benzimidazole derivatives | ZENECA LTD (GB) | 2001-10-31 | — | — | CN | disclosed |
| WO-2001056974-A2 | INHA INHIBITORS AND THEIR USE AS ANTIBACTERIALS | GENZYME CORPORATION (US) | 2001-08-09 | — | — | WO | disclosed |
| EP-1100798-A1 | BENZAZOLES: BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES | Zeneca Limited (GB) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000006566-A1 | BENZAZOLES: BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES | SYNGENTA LIMITED (GB) | 2000-02-10 | — | — | WO | disclosed |
| US-5834404-A | Substituted bicycloheptanedione derivative and herbicide | NIPPON SODA CO., LTD. (JP) | 1998-11-10 | — | — | US | disclosed |
| CN-1162953-A | Substituted bicycloheptanedione derivatives and herbicides | NIPPON SODA CO (JP) | 1997-10-22 | — | — | CN | disclosed |
| EP-0791572-A1 | SUBSTITUTED BICYCLOHEPTANEDIONE DERIVATIVE AND HERBICIDE | NIPPON SODA CO., LTD. (JP) | 1997-08-27 | — | — | EP | disclosed |
| EP-0306833-B1 | Silver halide photographic material | FUJI PHOTO FILM CO LTD (JP) | 1994-01-12 | — | — | EP | disclosed |
| US-5139919-A | With electron donating compound or precursor and a reducible dye-forming compound; positives, storage stable | FUJI PHOTO FILM CO., LTD. (JP) | 1992-08-18 | — | — | US | disclosed |
| US-5075208-A | Releasing a photographically useful compound upon reduction | FUJI PHOTO FILM CO., LTD. (JP) | 1991-12-24 | — | — | US | disclosed |
| US-5073473-A | Compound that releases a nucleating agent or a uv absorber | FUJI PHOTO FILM CO., LTD. (JP) | 1991-12-17 | — | — | US | disclosed |
| US-5071729-A | Discoloration inhibitor releasing compound | FUJI PHOTO FILM CO., LTD. (JP) | 1991-12-10 | — | — | US | disclosed |
| US-5064752-A | Silver halide photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1991-11-12 | — | — | US | disclosed |
| US-5049477-A | Image forming, etching, plating | FUJI PHOTO FILM CO., LTD. (JP) | 1991-09-17 | — | — | US | disclosed |
| US-4994363-A | Silver halide light-sensitive material containing a compound releasing a photographically useful group | FUJI PHOTO FILM CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| US-H830-H | CONTAINING A DESILVERING ACCELERATOR RELEASING COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1990-10-02 | — | — | US | disclosed |
| US-4956263-A | BLACKAND WHITE PHOTOGRAPHIC FILM CONTAINING CONTAINING A HYDRAZINE DERIVATIVE; HIGH CONTRAST; DAYLIGHT USE; ANTISOILANTS; SAFELIGHT SAFETY | FUJI PHOTO FILM CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| US-H817-H | Photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1990-09-04 | — | — | US | disclosed |
| US-4921785-A | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1990-05-01 | — | — | US | disclosed |
| US-4916047-A | POLYMERIC COMPOUND RELEASING USEFUL GROUP BY REDOX PROCESS TRIGGERED BY REDUCING AGENT | FUJI PHOTO FILM CO., LTD. (JP) | 1990-04-10 | — | — | US | disclosed |
| US-4877720-A | PHOTOGRAPHIC POLYMER WHICH UNDERGOES REDUCTION UPON DEVELOPMENT | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-31 | — | — | US | disclosed |
| US-4840887-A | USEFUL GROUP RELEASED BY CLEAVAGE BETWEEN SULFONYL GROUP AND A NITROGEN, SULFUR OR OXYGEN ATOM; STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1989-06-20 | — | — | US | disclosed |
| EP-0306833-A2 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1989-03-15 | — | — | EP | disclosed |
| US-4189428-A | DYEABILITY, COLORFASTNESS, RESISTANCE TO SUBLIMATION, IMPROVED BRIGHTNESS | EASTMAN KODAK COMPANY (US) | 1980-02-19 | — | — | US | disclosed |
| US-4140683-A | DISPERSE DYES FOR POLYESTERS | EASTMAN KODAK COMPANY (US) | 1979-02-20 | — | — | US | disclosed |
| US-4049643-A | DYES FOR POLYESTERS | EASTMAN KODAK COMPANY (US) | 1977-09-20 | — | — | US | disclosed |
| US-4006128-A | CELLULOSE ACETATES, VINYL POLYMERS, POLYOLEFINS, POLYESTERS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | disclosed |
| US-4006128-A | CELLULOSE ACETATES, VINYL POLYMERS, POLYOLEFINS, POLYESTERS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010189-A1 | beta-carboline derivatives useful as inhibitors of phosphodiesterase | PDE3B, PDE5A, PDE3A | ALDH1A1 198/4885PTGS2 596/4885ALDH3A1 460/4885 |
| US-20040209776-A1 | Azole derivatives useful as insecticide | CYP8B1, HRH2, API5 | ALDH1A1 1410/4885PTGS2 2067/4885ALDH3A1 1006/4885 |
| US-20030166641-A1 | Beta-carboline derivatives useful as inhibitors of phosphodiesterase | PDE3B, PDE5A, PDE3A | ALDH1A1 198/4885PTGS2 596/4885ALDH3A1 460/4885 |
| US-20070265231-A1 | Hydrazide Compounds for Combating Animal Pests | HRH4, CBR3, HRH2 | ALDH1A1 580/4885PTGS2 2130/4885ALDH3A1 461/4885 |
| US-20030092763-A1 | Method for induction of L-selectin shedding | PDIA5, PDIA4, PDIA6 | ALDH1A1 1261/4885PTGS2 198/4885ALDH3A1 552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.