Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.35 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12016624 | 1.00 | ALDH1A1 (0.36) | ALDH1A1TDP1TBXAS1EGLN3AHR | |
| SCHEMBL15465728 | 1.00 | ALDH1A1 (0.36) | ALDH1A1TDP1TBXAS1EGLN3AHR | |
| SCHEMBL15464597 | 1.00 | ALDH1A1 (0.36) | ALDH1A1TDP1TBXAS1EGLN3AHR | |
| SCHEMBL12016623 | 0.94 | ALDH1A1 (0.39) | ALDH1A1TDP1TBXAS1EGLN3AHR | |
| SCHEMBL15583426 | 0.93 | TBXAS1 (0.34) | ALDH1A1TDP1TBXAS1EGLN3AHR | |
| SCHEMBL19240712 | 0.92 | ABCB11 (0.35) | ALDH1A1TDP1TBXAS1AHRCYP24A1 | |
| SCHEMBL16214294 | 0.92 | ABCB11 (0.35) | ALDH1A1TDP1TBXAS1AHRCYP24A1 | |
| SCHEMBL12468229 | 0.92 | TDP1 (0.32) | ALDH1A1TDP1TBXAS1EGLN3AHR | |
| SCHEMBL12414787 | 0.92 | THRB (0.39) | ALDH1A1TDP1TBXAS1AHRCYP24A1 | |
| SCHEMBL16214299 | 0.89 | THRB (0.33) | ALDH1A1TDP1TBXAS1EGLN3AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9833520-B2 | Labeled, non-peptidic, multivalent integrin antagonist compounds; methods for synthesis and uses thereof | THE METHODIST HOSPITAL RESEARCH INSTITUTE (US) | 2017-12-05 | — | — | US | disclosed |
| US-20140044646-A1 | Labeled, Non-Peptidic, Multivalent Integrin Antagonist Compounds; Methods for Synthesis and Uses Thereof | THE METHODIST HOSPITAL RESEARCH INSTITUTE (US) | 2014-02-13 | — | — | US | disclosed |
| WO-2012103328-A1 | LABELED, NON- PEPTIDIC MULTIVALENT INTEGRIN ALPHA -V - BETA - 3 ANTAGONISTS, COMPOSITIONS CONTAINING THEM AND THEIR USE | THE METHODIST HOSPITAL RESEARCH INSTITUTE (US) | 2012-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140044646-A1 | Labeled, Non-Peptidic, Multivalent Integrin Antagonist Compounds; Methods for Synthesis and Uses Thereof | ITGB3, ITGAV, ITGB1 | ALDH1A1 2250/4885TDP1 4333/4885TBXAS1 1143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.