Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.50 |
| ▸ | STAMBP | O95630 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1928843 | 0.82 | SMN1; SMN2 (0.65) | SMN1; SMN2L3MBTL1LMNANPC1ALDH1A1 | |
| SCHEMBL12469174 | 0.81 | SIRT2 (0.61) | SMN1; SMN2LMNAMAPK1NPC1ALDH1A1 | |
| SCHEMBL24933996 | 0.78 | ALDH1A1 (0.47) | SMN1; SMN2LMNAMAPK1NPC1ALDH1A1 | |
| SCHEMBL30999881 | 0.78 | ALDH1A1 (0.47) | SMN1; SMN2LMNAMAPK1NPC1ALDH1A1 | |
| SCHEMBL12469032 | 0.77 | KMT2A (0.67) | SMN1; SMN2LMNAMAPK1MMP13ALDH1A1 | |
| SCHEMBL7082686 | 0.76 | TSHR (0.73) | SMN1; SMN2LMNAMAPK1MMP13NPC1 | |
| SCHEMBL11626565 | 0.76 | NPC1 (0.81) | SMN1; SMN2L3MBTL1LMNANPC1ALDH1A1 | |
| SCHEMBL5209577 | 0.76 | MMP13 (0.73) | SMN1; SMN2L3MBTL1LMNAMAPK1MMP13 | |
| SCHEMBL22501665 | 0.76 | MAPK1 (0.52) | MAPK1MMP13ALDH1A1TSHRKMT2A | |
| SCHEMBL13947589 | 0.76 | LMNA (0.78) | SMN1; SMN2L3MBTL1LMNAMMP13NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838534-A2 | SUBSTITUTED BENZAMIDES AND THEIR USES | The Board of Trustees of The Leland Stanford Junior University (US) | 2015-02-25 | — | — | EP | claimed |
| WO-2013155338-A2 | SUBSTITUTED BENZAMIDES AND THEIR USES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2013-10-17 | — | — | WO | claimed |
| EP-2627324-A2 | SUBSTITUTED BENZAMIDES AND THEIR USES | The Board of Trustees of The Leland Stanford Junior University (US) | 2013-08-21 | — | — | EP | disclosed |
| WO-2012051117-A2 | SUBSTITUTED BENZAMIDES AND THEIR USES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2012-04-19 | — | — | WO | disclosed |