Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2711034 | 0.84 | HTT (0.50) | KMT2AHTTUSP2ALDH1A1MAPK1 | |
| SCHEMBL12469175 | 0.80 | ALDH1A1 (0.59) | KMT2AHTTUSP2ALDH1A1MAPK1 | |
| SCHEMBL8432202 | 0.79 | USP2 (1.00) | KMT2AHTTUSP2ALDH1A1MAPK1 | |
| SCHEMBL12469027 | 0.77 | SMN1; SMN2 (0.57) | KMT2AHTTUSP2ALDH1A1MAPK1 | |
| SCHEMBL5572106 | 0.77 | GAA (0.44) | KMT2AHTTALDH1A1LMNAKDM4E | |
| SCHEMBL1399530 | 0.75 | USP2 (0.72) | KMT2AHTTUSP2ALDH1A1MEN1 | |
| SCHEMBL29392319 | 0.75 | USP2 (0.77) | KMT2AHTTUSP2ALDH1A1MEN1 | |
| SCHEMBL13161966 | 0.75 | USP2 (0.72) | KMT2AHTTUSP2ALDH1A1MAPK1 | |
| SCHEMBL11625657 | 0.75 | USP2 (0.72) | KMT2AHTTUSP2ALDH1A1MAPK1 | |
| SCHEMBL7535584 | 0.75 | USP2 (0.68) | KMT2AHTTUSP2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838534-A2 | SUBSTITUTED BENZAMIDES AND THEIR USES | The Board of Trustees of The Leland Stanford Junior University (US) | 2015-02-25 | — | — | EP | claimed |
| WO-2013155338-A2 | SUBSTITUTED BENZAMIDES AND THEIR USES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2013-10-17 | — | — | WO | claimed |
| EP-2627324-A2 | SUBSTITUTED BENZAMIDES AND THEIR USES | The Board of Trustees of The Leland Stanford Junior University (US) | 2013-08-21 | — | — | EP | disclosed |
| WO-2012051117-A2 | SUBSTITUTED BENZAMIDES AND THEIR USES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2012-04-19 | — | — | WO | disclosed |