Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 6/20 | 0.43 |
| ▸ | BTK | Q06187 | 9/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12469667 | 0.80 | BTK (0.43) | BTKGRM2 | |
| SCHEMBL12469647 | 0.78 | BTK (0.38) | BTKGRM2 | |
| SCHEMBL12469700 | 0.78 | BTK (0.40) | BTKGRM2 | |
| SCHEMBL12469593 | 0.78 | BTK (0.44) | BTKGRM2 | |
| SCHEMBL12469863 | 0.77 | BTK (0.42) | BTKGRM2 | |
| SCHEMBL12469435 | 0.77 | BTK (0.45) | BTKGRM2 | |
| SCHEMBL12469516 | 0.77 | GRM2 (0.40) | BTKGRM2 | |
| SCHEMBL12469765 | 0.77 | AURKA (0.40) | BTKGRM2 | |
| SCHEMBL12469609 | 0.76 | BTK (0.39) | BTKGRM2 | |
| SCHEMBL12469532 | 0.76 | BTK (0.42) | BTKGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047017-A2 | 2,3-DIHYDRO-ISOINDOL-1-ONE DERIVATIVE AND A COMPOSITION COMPRISING THE SAME | 크리스탈지노믹스(주) (KR) | 2012-04-12 | — | — | WO | disclosed |