Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | RORC | P51449 | 5/20 | 0.47 |
| ▸ | RORA | P35398 | 2/20 | 0.46 |
| ▸ | RORB | Q92753 | 2/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7140681 | 0.85 | NPC1 (0.53) | NPC1CNR2RORCRORARORB | |
| SCHEMBL19179039 | 0.80 | CYP1A2 (0.50) | NPC1CNR2RORCPTGER4CNR1 | |
| SCHEMBL26829115 | 0.80 | ALDH1A1 (0.43) | KDM4EALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL4779304 | 0.78 | PTGER4 (0.54) | NPC1CNR2RORCRORARORB | |
| SCHEMBL22618673 | 0.78 | KDM4E (0.44) | KDM4EALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL5795412 | 0.77 | CYP1A2 (0.54) | NPC1CNR2RORCRORARORB | |
| SCHEMBL12216223 | 0.76 | DHFR (0.61) | NPC1CNR2RORCRORARORB | |
| SCHEMBL16542755 | 0.76 | L3MBTL1 (0.37) | CNR2PTGER4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL17938383 | 0.75 | PTGER4 (0.56) | NPC1CNR2RORCRORARORB | |
| SCHEMBL21578475 | 0.75 | KDM4E (0.67) | KDM4EALDH1A1HSD17B10ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987472-B2 | N-cycloalkylalkyl triscarbazoles | SOLVAY SA (BE) | 2015-03-24 | — | — | US | disclosed |
| US-8987472-B2 | N-cycloalkylalkyl triscarbazoles | SOLVAY SA (BE) | 2015-03-24 | — | — | US | disclosed |
| EP-2627633-B1 | N-CYCLOALKYLALKYL TRISCARBAZOLES | Solvay Société Anonyme (BE) | 2015-03-04 | — | — | EP | disclosed |
| EP-2627633-B1 | N-CYCLOALKYLALKYL TRISCARBAZOLES | Solvay Société Anonyme (BE) | 2015-03-04 | — | — | EP | disclosed |
| EP-2627633-A1 | N-CYCLOALKYLALKYL TRISCARBAZOLES | SOLVAY (Société Anonyme) (BE) | 2013-08-21 | — | — | EP | disclosed |
| WO-2012048821-A1 | N-CYCLOALKYLALKYL TRISCARBAZOLES | SOLVAY SOCIETE ANONYME (BE) | 2012-04-19 | — | — | WO | disclosed |