Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12474364 | 0.85 | ALOX15 (0.36) | PPARGPPARAALOX15GFERADAM17 | |
| SCHEMBL4680033 | 0.81 | MRGPRX4 (0.40) | PPARGPPARAALOX15GFERADAM17 | |
| SCHEMBL20256607 | 0.81 | SLC6A4 (0.38) | PPARGPPARAALOX15GFERADAM17 | |
| SCHEMBL24587311 | 0.81 | PPARG (0.40) | PPARGPPARAALOX15GFERADAM17 | |
| SCHEMBL18585144 | 0.81 | MTNR1B (0.40) | PPARGPPARAALOX15GFERADAM17 | |
| SCHEMBL18216618 | 0.79 | P2RX7 (0.40) | PPARGPPARARORCMRGPRX4MTNR1B | |
| SCHEMBL24587369 | 0.79 | PPARG (0.40) | PPARGPPARAMTNR1BPKMHTT | |
| SCHEMBL20590929 | 0.78 | GPR3 (0.42) | RORCKDM4E | |
| SCHEMBL12474349 | 0.77 | CHRM2 (0.35) | PPARGPPARAALOX15GFERADAM17 | |
| SCHEMBL14596841 | 0.76 | ALOX15 (0.42) | PPARGPPARAALOX15GFERADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |