Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18585144 | 0.81 | MTNR1B (0.40) | PPARGPPARAALOX15GFERADAM17 | |
| SCHEMBL12474356 | 0.81 | PPARG (0.37) | PPARGPPARAALOX15GFERADAM17 | |
| SCHEMBL24587311 | 0.81 | PPARG (0.40) | PPARGPPARAALOX15GFERADAM17 | |
| SCHEMBL4680033 | 0.81 | MRGPRX4 (0.40) | PPARGPPARAALOX15GFERADAM17 | |
| SCHEMBL18216618 | 0.79 | P2RX7 (0.40) | PPARGPPARARORCMRGPRX4MTNR1B | |
| SCHEMBL24587369 | 0.79 | PPARG (0.40) | PPARGPPARAMTNR1B | |
| SCHEMBL4550397 | 0.78 | MPO (0.44) | MAOBALOX15AOC3 | |
| SCHEMBL29786515 | 0.78 | MPO (0.44) | MAOBALOX15AOC3 | |
| SCHEMBL12474349 | 0.77 | CHRM2 (0.35) | PPARGPPARAALOX15GFERADAM17 | |
| SCHEMBL3536393 | 0.77 | TAAR1 (0.55) | TAAR1MTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018106284-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2018-06-14 | — | — | WO | disclosed |