Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 6/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1846872 | 0.85 | ALOX5 (0.56) | TYRALOX5MEN1MAPTKMT2A | |
| SCHEMBL30576433 | 0.85 | ALOX5 (0.56) | TYRALOX5MEN1MAPTKMT2A | |
| SCHEMBL9130083 | 0.82 | HRH1 (0.52) | HSP90AA1HRH1ALDH1A1LMNAALOX15 | |
| SCHEMBL5669241 | 0.80 | MAPT (0.53) | TYRALOX5MEN1MAPTKMT2A | |
| SCHEMBL28075033 | 0.80 | CCR5 (0.48) | TYRALOX5MEN1MAPTKMT2A | |
| SCHEMBL1397158 | 0.78 | TYR (1.00) | TYRALOX5MEN1MAPTKMT2A | |
| SCHEMBL24201406 | 0.76 | TYR (0.78) | TYRALOX5MEN1MAPTKMT2A | |
| SCHEMBL230753 | 0.75 | HRH1 (0.73) | HRH1MAPTALDH1A1LMNAALOX15 | |
| SCHEMBL29485678 | 0.75 | HRH1 (0.73) | HRH1MAPTALDH1A1LMNAALOX15 | |
| SCHEMBL1772721 | 0.75 | CYP1A2 (0.56) | HRH1KDM4EALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673261-A1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | Pierre Fabre Dermo-Cosmétique (FR) | 2013-12-18 | — | — | EP | disclosed |
| WO-2012107421-A1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2012-08-16 | — | — | WO | disclosed |