Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12477101 | 1.00 | KDM4E (0.43) | KDM4EALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL4928069 | 0.81 | MAOA (0.48) | KDM4EALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL10972894 | 0.81 | MAOA (0.48) | KDM4EALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL14128964 | 0.78 | KDM4E (0.45) | KDM4EALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL14129022 | 0.77 | KDM4E (0.42) | KDM4EALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL14128965 | 0.76 | ALDH1A1 (0.49) | KDM4EALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL29257714 | 0.76 | MAPT (0.39) | KDM4EALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL7262462 | 0.75 | RAB9A (0.55) | KDM4EALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL7262459 | 0.75 | RAB9A (0.55) | KDM4EALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL28089833 | 0.75 | KDM4E (0.55) | KDM4EALDH1A1MAPTRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103459387-B | Mesoionic pyrido [1,2-A ] pyrimidines as pesticides | DUPONT (US) | 2015-08-26 | — | — | CN | claimed |
| EP-2658856-B1 | MESOIONIC PYRIDO [1,2-A] PYRIMIDINE PESTICIDES | DU PONT (US) | 2015-02-25 | — | — | EP | claimed |
| US-8895738-B2 | Mesoionic pyrido [1, 2-A] pyrimidine pesticides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-11-25 | — | — | US | claimed |
| US-20130190171-A1 | MESOIONIC PYRIDO [1, 2-A] PYRIMIDINE PESTICIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-07-25 | — | — | US | claimed |
| EP-2791107-B1 | MALONIC ACID DI-SALTS AND A METHOD FOR PREPARING MALONYL DIHALIDES | FMC CORP (US) | 2019-03-13 | — | — | EP | disclosed |
| WO-2017189339-A1 | PROCESS FOR THE PREPARATION OF N-[(5-PYRIMIDINYL)METHYL]-2-PYRIDINAMINES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-11-02 | — | — | WO | disclosed |
| CN-105198874-A | Mesoionic Pyrido [1,2 -A] Pyrimidine Pesticides | DU PONT | 2015-12-30 | — | — | CN | disclosed |
| CN-103459387-B | Mesoionic pyrido [1,2-A ] pyrimidines as pesticides | DUPONT (US) | 2015-08-26 | — | — | CN | disclosed |
| US-9108965-B2 | Malonic acid di-salts and a method for preparing malonyl dihalides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-08-18 | — | — | US | disclosed |
| EP-2658856-B1 | MESOIONIC PYRIDO [1,2-A] PYRIMIDINE PESTICIDES | DU PONT (US) | 2015-02-25 | — | — | EP | disclosed |
| US-20150038329-A1 | MESOIONIC PESTICIDES | DU PONT (US) | 2015-02-05 | — | — | US | disclosed |
| US-8895738-B2 | Mesoionic pyrido [1, 2-A] pyrimidine pesticides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-11-25 | — | — | US | disclosed |
| US-20140343284-A1 | MALONIC ACID DI-SALTS AND A METHOD FOR PREPARING MALONYL DIHALIDES | FMC CORPORATION | 2014-11-20 | — | — | US | disclosed |
| EP-2791107-A1 | MALONIC ACID DI-SALTS AND A METHOD FOR PREPARING MALONYL DIHALIDES | E. I. Du Pont de Nemours and Company (US) | 2014-10-22 | — | — | EP | disclosed |
| EP-2658856-A1 | MESOIONIC PYRIDO [1,2 -A]PYRIMIDINE PESTICIDES | E.I. Du Pont De Nemours And Company (US) | 2013-11-06 | — | — | EP | disclosed |
| US-20130190171-A1 | MESOIONIC PYRIDO [1, 2-A] PYRIMIDINE PESTICIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-07-25 | — | — | US | disclosed |
| WO-2013090547-A1 | MALONIC ACID DI-SALTS AND A METHOD FOR PREPARING MALONYL DIHALIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-20 | — | — | WO | disclosed |
| WO-2012092115-A1 | MESOIONIC PYRIDO [1,2 -A] PYRIMIDINE PESTICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140343284-A1 | MALONIC ACID DI-SALTS AND A METHOD FOR PREPARING MALONYL DIHALIDES | ME1, DDT, ME3 | KDM4E 1104/4885ALDH1A1 116/4885MAPT 4432/4885 |
| US-20150038329-A1 | MESOIONIC PESTICIDES | C5, DDT, CBR3 | KDM4E 862/4885ALDH1A1 1406/4885MAPT 4446/4885 |
| US-20130190171-A1 | MESOIONIC PYRIDO [1, 2-A] PYRIMIDINE PESTICIDES | PNPO, C5, CBR3 | KDM4E 1164/4885ALDH1A1 1157/4885MAPT 4369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.