Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 8/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5433423 | 0.84 | ALOX5 (0.54) | ALOX5MAOBCYP4F2CYP4A11LMNA | |
| SCHEMBL27696607 | 0.83 | MAOB (0.58) | ALOX5MAOBLMNACYP1A2PTGS1 | |
| SCHEMBL16048596 | 0.81 | ALOX5 (0.51) | ALOX5MAOBLMNACYP1A2PTGS1 | |
| SCHEMBL15968723 | 0.77 | LMNA (0.61) | ALOX5MAOBCYP4F2CYP4A11LMNA | |
| SCHEMBL28874699 | 0.76 | MAOB (0.58) | MAOBAPPGAAMAPTSMN1; SMN2 | |
| SCHEMBL306550 | 0.76 | LMNA (0.64) | ALOX5MAOBLMNACYP1A2PTGS1 | |
| SCHEMBL31601164 | 0.76 | MAOB (0.58) | ALOX5MAOBLMNACYP1A2PTGS1 | |
| SCHEMBL16822445 | 0.76 | ALOX5 (0.56) | ALOX5MAOBLMNACYP1A2PTGS1 | |
| SCHEMBL28943690 | 0.76 | ALOX5 (0.56) | ALOX5MAOBCYP4F2CYP4A11LMNA | |
| SCHEMBL31725938 | 0.76 | ALOX5 (0.56) | ALOX5MAOBLMNACYP1A2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9284270-B2 | Boronic acid catalysts and methods of use thereof for activation and transformation of carboxylic acids | THE GOVERNERS OF THE UNIVERSITY OF ALBERTA (CA) | 2016-03-15 | — | — | US | disclosed |
| US-20140142322-A1 | Boronic Acid Catalysts and Methods of Use Thereof for Activation and Transformation of Carboxylic Acids | GREENCENTRE CANADA (CA) | 2014-05-22 | — | — | US | disclosed |
| EP-2675816-A1 | BORONIC ACID CATALYSTS AND METHODS OF USE THEREOF FOR ACTIVATION AND TRANSFORMATION OF CARBOXYLIC ACIDS | The Governors of the University of Alberta (CA) | 2013-12-25 | — | — | EP | disclosed |
| WO-2012109749-A1 | BORONIC ACID CATALYSTS AND METHODS OF USE THEREOF FOR ACTIVATION AND TRANSFORMATION OF CARBOXYLIC ACIDS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2012-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140142322-A1 | Boronic Acid Catalysts and Methods of Use Thereof for Activation and Transformation of Carboxylic Acids | BCAT1, ME1, BCAT2 | ALOX5 465/4885MAOB 36/4885CYP4F2 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.