Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.39 |
| ▸ | APLNR | P35414 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12481039 | 0.94 | SMN1; SMN2 (0.38) | SMN1; SMN2RAPGEF4APLNRALDH1A1L3MBTL1 | |
| SCHEMBL15341173 | 0.92 | RAPGEF4 (0.41) | SMN1; SMN2RAPGEF4APLNRALDH1A1L3MBTL1 | |
| SCHEMBL12481815 | 0.86 | APLNR (0.39) | SMN1; SMN2RAPGEF4APLNRALDH1A1L3MBTL1 | |
| SCHEMBL469842 | 0.86 | RAPGEF4 (0.42) | SMN1; SMN2RAPGEF4APLNRALDH1A1L3MBTL1 | |
| SCHEMBL12481817 | 0.82 | RAPGEF4 (0.36) | SMN1; SMN2RAPGEF4APLNRALDH1A1L3MBTL1 | |
| SCHEMBL12481505 | 0.77 | IDO1 (0.35) | SMN1; SMN2LMNAHPGD | |
| SCHEMBL469870 | 0.72 | CDK8 (0.35) | SMN1; SMN2ALDH1A1LMNAHPGDMAPT | |
| SCHEMBL15333651 | 0.72 | PKM (0.39) | SMN1; SMN2ALDH1A1L3MBTL1LMNAHPGD | |
| SCHEMBL15341141 | 0.72 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1LMNAHPGDGAA | |
| SCHEMBL15344249 | 0.70 | SMN1; SMN2 (0.34) | SMN1; SMN2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029295-B2 | Pyridazinone compound and herbicide and noxious arthropod controlling agent comprising it | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-05-12 | — | — | US | disclosed |
| US-9029295-B2 | Pyridazinone compound and herbicide and noxious arthropod controlling agent comprising it | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-05-12 | — | — | US | disclosed |
| US-9029295-B2 | Pyridazinone compound and herbicide and noxious arthropod controlling agent comprising it | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-05-12 | — | — | US | disclosed |
| EP-2658845-B1 | PYRIDAZINONE COMPOUND AND HERBICIDE AND NOXIOUS ARTHROPOD CONTROLLING AGENT COMPRISING IT | SUMITOMO CHEMICAL CO (JP) | 2015-02-25 | — | — | EP | disclosed |
| EP-2658845-B1 | PYRIDAZINONE COMPOUND AND HERBICIDE AND NOXIOUS ARTHROPOD CONTROLLING AGENT COMPRISING IT | SUMITOMO CHEMICAL CO (JP) | 2015-02-25 | — | — | EP | disclosed |
| EP-2658845-A1 | PYRIDAZINONE COMPOUND AND HERBICIDE AND NOXIOUS ARTHROPOD CONTROLLING AGENT COMPRISING IT | Sumitomo Chemical Company Limited (JP) | 2013-11-06 | — | — | EP | disclosed |
| US-20130281299-A1 | PYRIDAZINONE COMPOUND AND HERBICIDE AND NOXIOUS ARTHROPOD CONTROLLING AGENT COMPRISING IT | SUMITOMO CHEMICAL COMPANY,LIMITED (JP) | 2013-10-24 | — | — | US | disclosed |
| US-20130281299-A1 | PYRIDAZINONE COMPOUND AND HERBICIDE AND NOXIOUS ARTHROPOD CONTROLLING AGENT COMPRISING IT | SUMITOMO CHEMICAL COMPANY,LIMITED (JP) | 2013-10-24 | — | — | US | disclosed |
| US-20130281299-A1 | PYRIDAZINONE COMPOUND AND HERBICIDE AND NOXIOUS ARTHROPOD CONTROLLING AGENT COMPRISING IT | SUMITOMO CHEMICAL COMPANY,LIMITED (JP) | 2013-10-24 | — | — | US | disclosed |
| WO-2012091156-A1 | PYRIDAZINONE COMPOUND AND HERBICIDE AND NOXIOUS ARTHROPOD CONTROLLING AGENT COMPRISING IT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281299-A1 | PYRIDAZINONE COMPOUND AND HERBICIDE AND NOXIOUS ARTHROPOD CONTROLLING AGENT COMPRISING IT | ACHE, CBR3, DDT | SMN1; SMN2 2614/4885RAPGEF4 2881/4885APLNR 2987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.