Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | GSK3B | P49841 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | AKT2 | P31751 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1846809 | 0.90 | PRKAA2 (0.42) | KDM4CKDM4AKDM5AKDM5BGAA | |
| SCHEMBL1847418 | 0.79 | PRKAA2 (0.44) | KDM4CKDM4AKDM5AKDM5BGAA | |
| SCHEMBL1725767 | 0.75 | GSK3B (0.45) | ACHEGSK3BBCHEMCHR1 | |
| SCHEMBL1726693 | 0.75 | MCHR1 (0.38) | ACHEGSK3BBCHEHTR2AMCHR1 | |
| SCHEMBL1846811 | 0.74 | MCHR1 (0.47) | ACHEGSK3BBCHEHTR2AMCHR1 | |
| SCHEMBL12482193 | 0.74 | OPRM1 (0.42) | ACHEHTR2AMCHR1CHRM4CYP2D6 | |
| SCHEMBL12482196 | 0.73 | MCHR1 (0.37) | ACHEGSK3BBCHEHTR2AMCHR1 | |
| SCHEMBL1035443 | 0.68 | AKT1 (0.41) | KDM4CKDM4AKDM5AKDM5BAKT1 | |
| SCHEMBL1844021 | 0.67 | WNK1 (0.43) | — | |
| SCHEMBL1726547 | 0.66 | GSK3B (0.48) | ACHEGSK3BBCHEMCHR1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037282-A3 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. (US) | 2012-05-10 | — | — | WO | disclosed |