Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
| ▸ | GSK3B | P49841 | 4/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12482191 | 0.90 | KDM4C (0.40) | KDM4CKDM4AKDM5AKDM5BACHE | |
| SCHEMBL1847418 | 0.88 | PRKAA2 (0.44) | PRKAA2GRM2KDM4CKDM4AKDM5A | |
| SCHEMBL1035443 | 0.77 | AKT1 (0.41) | PRKAA2GRM2KDM4CKDM4AKDM5A | |
| SCHEMBL1844021 | 0.76 | WNK1 (0.43) | OPRK1 | |
| SCHEMBL1725767 | 0.76 | GSK3B (0.45) | ACHEGSK3BBCHE | |
| SCHEMBL1726693 | 0.75 | MCHR1 (0.38) | ACHEGSK3BBCHECDK9 | |
| SCHEMBL1846811 | 0.75 | MCHR1 (0.47) | ACHEGSK3BBCHE | |
| SCHEMBL12482193 | 0.74 | OPRM1 (0.42) | OPRM1ACHE | |
| SCHEMBL12482196 | 0.73 | MCHR1 (0.37) | GRM2ACHEGSK3BBCHE | |
| SCHEMBL1031736 | 0.73 | STAT3 (0.41) | PRKAA2OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2324010-A1 | INSECTICIDAL PHENYL- OR PYRIDYL-PIPERIDINE COMPOUNDS | Syngenta Participations AG (CH) | 2011-05-25 | — | — | EP | disclosed |