Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HNF4A | P41235 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15477079 | 1.00 | ALDH1A1 (0.59) | ALDH1A1LMNAMAPTL3MBTL1HNF4A | |
| SCHEMBL31278212 | 0.79 | ALDH1A1 (0.74) | ALDH1A1LMNAMAPTL3MBTL1HNF4A | |
| SCHEMBL3616574 | 0.79 | ALDH1A1 (0.74) | ALDH1A1LMNAMAPTL3MBTL1HNF4A | |
| SCHEMBL130160 | 0.79 | TRPA1 (0.44) | TRPA1 | |
| Hydrochloric Acid SCHEMBL2402126 | 0.77 | ALDH1A1 (0.71) | ALDH1A1LMNAMAPTL3MBTL1HNF4A | |
| Hydrochloric Acid SCHEMBL15366836 | 0.77 | ALDH1A1 (0.71) | ALDH1A1LMNAMAPTL3MBTL1HNF4A | |
| SCHEMBL69716 | 0.77 | ALDH1A1 (0.69) | ALDH1A1LMNAMAPTL3MBTL1HNF4A | |
| SCHEMBL2780740 | 0.76 | PDK2 (0.39) | ALDH1A1LMNAMAPTMEN1GAA | |
| SCHEMBL581124 | 0.74 | ALDH1A1 (1.00) | ALDH1A1LMNAMAPTL3MBTL1POLB | |
| SCHEMBL5089936 | 0.74 | ALDH1A1 (0.66) | ALDH1A1LMNAMAPTL3MBTL1HNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9790484-B2 | Silica encapsulated biomaterials | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2017-10-17 | — | — | US | disclosed |
| CN-103917098-A | Silica encapsulated biomaterials | UNIV MINNESOTA | 2014-07-09 | — | — | CN | disclosed |
| US-20140051144-A1 | SILICA ENCAPSULATED BIOMATERIALS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2014-02-20 | — | — | US | disclosed |
| WO-2012116013-A2 | SILICA ENCAPSULATED BIOMATERIALS | WACKETT LAWRENCE P (US) | 2012-08-30 | — | — | WO | disclosed |