Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | BCHE | P06276 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12493420 | 0.92 | ALDH1A1 (0.55) | MAOBBCHETDP1ALDH1A1MAPK1 | |
| SCHEMBL12494016 | 0.87 | ALDH1A1 (0.62) | TDP1ALDH1A1MAPK1PTK2BTP53 | |
| SCHEMBL12494013 | 0.82 | SMN1; SMN2 (0.50) | MAOBALDH1A1MAPK1PTK2BTP53 | |
| SCHEMBL12494308 | 0.82 | SMN1; SMN2 (0.66) | ALDH1A1MAPK1PTK2BTP53SMN1; SMN2 | |
| SCHEMBL12493512 | 0.81 | MRGPRX4 (0.53) | TDP1ALDH1A1MAPK1PTK2BTP53 | |
| SCHEMBL12492802 | 0.81 | ALDH1A1 (0.54) | TDP1ALDH1A1MAPK1PTK2BTP53 | |
| SCHEMBL12492811 | 0.79 | ALDH1A1 (0.53) | TDP1ALDH1A1MAPK1PTK2BTP53 | |
| SCHEMBL12493367 | 0.79 | SMN1; SMN2 (0.52) | TDP1ALDH1A1MAPK1PTK2BTP53 | |
| SCHEMBL12700064 | 0.77 | APLNR (0.49) | MAOBTDP1ALDH1A1MAPK1PTK2B | |
| SCHEMBL14416964 | 0.77 | MAOB (0.53) | MAOBBCHEALDH1A1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2683703-B1 | NOVEL SUBSTITUTED PHENYL-OXATHIAZINE DERIVATIVES, METHOD FOR PRODUCING THEM, DRUGS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | SANOFI SA (FR) | 2015-05-27 | — | — | EP | disclosed |
| EP-2683703-B1 | NOVEL SUBSTITUTED PHENYL-OXATHIAZINE DERIVATIVES, METHOD FOR PRODUCING THEM, DRUGS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | SANOFI SA (FR) | 2015-05-27 | — | — | EP | disclosed |
| US-8895547-B2 | Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof | SANOFI (FR) | 2014-11-25 | — | — | US | disclosed |
| US-8895547-B2 | Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof | SANOFI (FR) | 2014-11-25 | — | — | US | disclosed |
| EP-2683703-A1 | NOVEL SUBSTITUTED PHENYL-OXATHIAZINE DERIVATIVES, METHOD FOR PRODUCING THEM, DRUGS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | SANOFI (FR) | 2014-01-15 | — | — | EP | disclosed |
| WO-2012120057-A1 | NOVEL SUBSTITUTED PHENYL-OXATHIAZINE DERIVATIVES, METHOD FOR PRODUCING THEM, DRUGS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | SANOFI (FR) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012120057-A1 | NOVEL SUBSTITUTED PHENYL-OXATHIAZINE DERIVATIVES, METHOD FOR PRODUCING THEM, DRUGS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | SANOFI (FR) | 2012-09-13 | — | — | WO | disclosed |