Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.51 |
| ▸ | APLNR | P35414 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12494016 | 0.92 | ALDH1A1 (0.62) | ALDH1A1MAPK1PTK2BMEN1KMT2A | |
| SCHEMBL12493420 | 0.88 | ALDH1A1 (0.55) | ALDH1A1MAPK1PTK2BMEN1KMT2A | |
| SCHEMBL12494088 | 0.85 | APLNR (0.52) | ALDH1A1MAPK1PTK2BMEN1KMT2A | |
| SCHEMBL12493897 | 0.85 | APLNR (0.52) | ALDH1A1MAPK1PTK2BMEN1KMT2A | |
| SCHEMBL12493486 | 0.84 | L3MBTL1 (0.54) | ALDH1A1MAPK1PTK2BMEN1KMT2A | |
| SCHEMBL12493991 | 0.82 | APLNR (0.49) | ALDH1A1MAPK1PTK2BMEN1KMT2A | |
| SCHEMBL12494428 | 0.82 | APLNR (0.49) | ALDH1A1MAPK1PTK2BMEN1KMT2A | |
| SCHEMBL12700064 | 0.82 | APLNR (0.49) | ALDH1A1MAPK1PTK2BMEN1KMT2A | |
| SCHEMBL12492811 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MAPK1PTK2BMEN1KMT2A | |
| SCHEMBL12493445 | 0.81 | MAOB (0.53) | ALDH1A1MAPK1PTK2BTP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2683703-B1 | NOVEL SUBSTITUTED PHENYL-OXATHIAZINE DERIVATIVES, METHOD FOR PRODUCING THEM, DRUGS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | SANOFI SA (FR) | 2015-05-27 | — | — | EP | disclosed |
| EP-2683703-B1 | NOVEL SUBSTITUTED PHENYL-OXATHIAZINE DERIVATIVES, METHOD FOR PRODUCING THEM, DRUGS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | SANOFI SA (FR) | 2015-05-27 | — | — | EP | disclosed |
| US-8895547-B2 | Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof | SANOFI (FR) | 2014-11-25 | — | — | US | disclosed |
| US-8895547-B2 | Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof | SANOFI (FR) | 2014-11-25 | — | — | US | disclosed |
| EP-2683703-A1 | NOVEL SUBSTITUTED PHENYL-OXATHIAZINE DERIVATIVES, METHOD FOR PRODUCING THEM, DRUGS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | SANOFI (FR) | 2014-01-15 | — | — | EP | disclosed |
| WO-2012120057-A1 | NOVEL SUBSTITUTED PHENYL-OXATHIAZINE DERIVATIVES, METHOD FOR PRODUCING THEM, DRUGS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | SANOFI (FR) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012120057-A1 | NOVEL SUBSTITUTED PHENYL-OXATHIAZINE DERIVATIVES, METHOD FOR PRODUCING THEM, DRUGS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | SANOFI (FR) | 2012-09-13 | — | — | WO | disclosed |