Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12493420 | 0.85 | ALDH1A1 (0.55) | APLNRTP53ALDH1A1MAPK1PTK2B | |
| SCHEMBL12494088 | 0.84 | APLNR (0.52) | APLNRTP53ALDH1A1MAPK1PTK2B | |
| SCHEMBL12493897 | 0.84 | APLNR (0.52) | APLNRTP53ALDH1A1MAPK1PTK2B | |
| SCHEMBL12494016 | 0.84 | ALDH1A1 (0.62) | APLNRTP53ALDH1A1MAPK1PTK2B | |
| SCHEMBL12492802 | 0.82 | ALDH1A1 (0.54) | APLNRTP53ALDH1A1MAPK1PTK2B | |
| SCHEMBL12493991 | 0.81 | APLNR (0.49) | APLNRTP53ALDH1A1MAPK1PTK2B | |
| SCHEMBL12494428 | 0.81 | APLNR (0.49) | APLNRTP53ALDH1A1MAPK1PTK2B | |
| SCHEMBL12493486 | 0.81 | L3MBTL1 (0.54) | APLNRTP53ALDH1A1MAPK1PTK2B | |
| SCHEMBL28452492 | 0.79 | APLNR (0.63) | APLNRTP53ALDH1A1MEN1KMT2A | |
| SCHEMBL8688214 | 0.79 | APLNR (0.53) | APLNRTP53ALDH1A1MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895547-B2 | Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof | SANOFI (FR) | 2014-11-25 | — | — | US | disclosed |
| WO-2012120057-A1 | NOVEL SUBSTITUTED PHENYL-OXATHIAZINE DERIVATIVES, METHOD FOR PRODUCING THEM, DRUGS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | SANOFI (FR) | 2012-09-13 | — | — | WO | disclosed |