Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | FABP4 | P15090 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12493367 | 0.91 | SMN1; SMN2 (0.52) | MRGPRX4SMN1; SMN2TP53RAB9AMEN1 | |
| SCHEMBL12494016 | 0.86 | ALDH1A1 (0.62) | SMN1; SMN2TP53MEN1KMT2AALDH1A1 | |
| SCHEMBL12494013 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2TP53MEN1KMT2AALDH1A1 | |
| SCHEMBL12494308 | 0.83 | SMN1; SMN2 (0.66) | SMN1; SMN2TP53MEN1KMT2AALDH1A1 | |
| SCHEMBL12493445 | 0.81 | MAOB (0.53) | SMN1; SMN2TP53PPARAALDH1A1MAPK1 | |
| SCHEMBL12493991 | 0.81 | APLNR (0.49) | SMN1; SMN2TP53RAB9AMEN1KMT2A | |
| SCHEMBL12493486 | 0.81 | L3MBTL1 (0.54) | SMN1; SMN2TP53AKR1C3MEN1KMT2A | |
| SCHEMBL12493420 | 0.80 | ALDH1A1 (0.55) | SMN1; SMN2TP53PPARAMEN1KMT2A | |
| SCHEMBL12492802 | 0.79 | ALDH1A1 (0.54) | TP53MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL12494088 | 0.79 | APLNR (0.52) | SMN1; SMN2TP53MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2683703-B1 | NOVEL SUBSTITUTED PHENYL-OXATHIAZINE DERIVATIVES, METHOD FOR PRODUCING THEM, DRUGS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | SANOFI SA (FR) | 2015-05-27 | — | — | EP | disclosed |
| EP-2683703-B1 | NOVEL SUBSTITUTED PHENYL-OXATHIAZINE DERIVATIVES, METHOD FOR PRODUCING THEM, DRUGS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | SANOFI SA (FR) | 2015-05-27 | — | — | EP | disclosed |
| US-8895547-B2 | Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof | SANOFI (FR) | 2014-11-25 | — | — | US | disclosed |
| US-8895547-B2 | Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof | SANOFI (FR) | 2014-11-25 | — | — | US | disclosed |
| EP-2683703-A1 | NOVEL SUBSTITUTED PHENYL-OXATHIAZINE DERIVATIVES, METHOD FOR PRODUCING THEM, DRUGS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | SANOFI (FR) | 2014-01-15 | — | — | EP | disclosed |
| WO-2012120057-A1 | NOVEL SUBSTITUTED PHENYL-OXATHIAZINE DERIVATIVES, METHOD FOR PRODUCING THEM, DRUGS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | SANOFI (FR) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012120057-A1 | NOVEL SUBSTITUTED PHENYL-OXATHIAZINE DERIVATIVES, METHOD FOR PRODUCING THEM, DRUGS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | SANOFI (FR) | 2012-09-13 | — | — | WO | disclosed |