SCHEMBL1250604

SCHEMBL1250604

C=C(C)C(=O)N(O)CCC

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
TSHR P16473 3/20 0.32
MAPK1 P28482 1/20 0.32
FDPS P14324 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
KDM5A P29375 1/20 0.31
KDM4C Q9H3R0 1/20 0.31
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278338 0.87 TDP1 (0.36) TSHRTDP1ALDH1A1
SCHEMBL28346437 0.86 CA12 (0.39) CA12CA9TSHRKDM5AKDM4C
SCHEMBL27873052 0.83 TSHR (0.44) TSHRKDM5AKDM4C
Phenol SCHEMBL28090452 0.82 ALOX5 (0.42) CA12CA2CA9TDP1ALDH1A1
SCHEMBL11345617 0.81 MAPT (0.32) TDP1
SCHEMBL2221793 0.80
SCHEMBL154162 0.78 CA12 (0.46) CA12CA2CA9TSHRMAPK1
SCHEMBL375727 0.76 CA12 (0.34) CA12CA2CA9TSHRMAPK1
SCHEMBL28124857 0.74 TSHR (0.34) CA12CA9TSHRKDM5AKDM4C
SCHEMBL375752 0.74 CA12 (0.43) CA12CA2CA9TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2777723-B1 Implantable object comprising selectively degradable copolymers for improved explantability BIOTRONIK AG (CH) 2017-12-20 EP claimed
EP-2136851-B1 A COATING OF FAST ABSORPTION OR DISSOLUTION ABBOTT CARDIOVASCULAR SYSTEMS INC (US) 2017-09-06 EP claimed
US-20140079742-A1 COATING OF FAST ABSORPTION OR DISSOLUTION ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2014-03-20 US claimed
US-20140074224-A1 COATING OF FAST ABSORPTION OR DISSOLUTION ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2014-03-13 US claimed
EP-2136851-A2 A COATING OF FAST ABSORPTION OR DISSOLUTION Abbott Cardiovascular Systems, Inc. (US) 2009-12-30 EP claimed
WO-2008076731-A2 A COATING OF FAST ABSORPTION OR DISSOLUTION ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2008-06-26 WO claimed
US-20080145393-A1 Coating of fast absorption or dissolution ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2008-06-19 US claimed
JP-2008500104-A 2008-01-10 JP claimed
EP-1755699-A1 HEPARIN CONTAINING BLOCK COPOLYMERS COATED ON IMPLANTS LIKE STENTS ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2007-02-28 EP claimed
WO-2005118018-A1 HEPARIN CONTAINING BLOCK COPOLYMERS COATED ON IMPLANTS LIKE STENTS ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2005-12-15 WO claimed
US-20050266038-A1 Antifouling heparin coatings ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2005-12-01 US claimed
CN-117396497-A Use of long acting growth hormone for the treatment of inflammation induced diseases 阿森迪斯药物股份有限公司 2024-01-12 CN disclosed
CN-109843295-B Combination therapy with controlled release of CNP agonist 阿森迪斯药物生长障碍股份有限公司 2022-04-05 CN disclosed
CN-107405409-B CNP prodrugs 阿森迪斯药物生长障碍股份有限公司 2022-03-22 CN disclosed
CN-109789189-A Dosage regimen for controlled release of PTH compounds 阿森迪斯药物骨疾病股份有限公司 2019-05-21 CN disclosed
WO-2005000894-A2 BINDING MOLECULES FOR THE TREATMENT OF MYELOID CELL MALIGNANCIES CRUCELL HOLLAND B.V. (NL) 2005-01-06 WO disclosed
WO-2004067569-A1 INTERNALISING HUMAN BINDING MOLECULES AGAINST CD72 CRUCELL HOLLAND B.V. (NL) 2004-08-12 WO disclosed
CN-1419593-A Adhesive system comprising etherified amino resins AKZO NOBEL NV (NL) 2003-05-21 CN disclosed
EP-1220657-A1 LIPOSOME ENCAPSULATED SILVER SALT COMPOSITIONS 1170535 Ontario Inc. (CA) 2002-07-10 EP disclosed
WO-2001026627-A1 LIPOSOME ENCAPSULATED SILVER SALT COMPOSITIONS 1170535 ONTARIO INC. (CA) 2001-04-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080145393-A1 Coating of fast absorption or dissolution TNNC1, SLC10A2, SI CA12 74/4885CA2 1650/4885CA9 183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.