Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4426973 | 0.84 | CTSK (0.51) | CTSKCTSSMMP1MMP3MMP9 | |
| SCHEMBL12433264 | 0.84 | CTSK (0.51) | CTSKCTSSMMP1MMP3MMP9 | |
| SCHEMBL29401894 | 0.80 | GGT1 (0.56) | CTSKCTSSMMP1MMP3MMP9 | |
| SCHEMBL8254030 | 0.79 | CCKBR (0.49) | — | |
| SCHEMBL15384071 | 0.77 | CTSK (0.48) | CTSKCTSSMMP1MMP3MMP9 | |
| SCHEMBL19839686 | 0.76 | MEN1 (0.55) | CTSKMMP1MMP3MMP9MEN1 | |
| SCHEMBL19839675 | 0.76 | MEN1 (0.55) | CTSKMMP1MMP3MMP9MEN1 | |
| SCHEMBL19839673 | 0.76 | MEN1 (0.55) | CTSKMMP1MMP3MMP9MEN1 | |
| SCHEMBL7440534 | 0.76 | CTSK (0.55) | CTSKCTSSMMP1MMP3MMP9 | |
| SCHEMBL12890796 | 0.76 | CTSK (0.65) | CTSKCTSSMMP1MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7981922-B2 | Angiotensin I-converting enzyme (ACE) inhibitors | UNIVERSITY OF CAPE TOWN (ZA) | 2011-07-19 | — | — | US | disclosed |