Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9349279 | 0.87 | MTNR1A (0.53) | MTNR1AMTNR1BPPARGSMN1; SMN2ALOX15 | |
| SCHEMBL1252550 | 0.86 | MAPT (0.50) | SMN1; SMN2MAPTLMNAHTTALOX15 | |
| SCHEMBL2498213 | 0.83 | SMN1; SMN2 (0.60) | PPARGSMN1; SMN2LMNAALDH1A1TSHR | |
| SCHEMBL12061827 | 0.82 | ALOX5 (0.48) | MTNR1BSMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL9832657 | 0.81 | SMN1; SMN2 (0.47) | MTNR1AMTNR1BPPARGSMN1; SMN2MAPT | |
| SCHEMBL4275474 | 0.81 | TSHR (0.43) | PPARGMAPTLMNAHTTALOX15 | |
| SCHEMBL16212493 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTLMNAHTTALDH1A1 | |
| SCHEMBL6365445 | 0.80 | MTNR1A (0.54) | MTNR1AMTNR1BSMN1; SMN2MAPTLMNA | |
| SCHEMBL19347238 | 0.80 | ALDH1A1 (0.54) | MTNR1AMTNR1BSMN1; SMN2MAPTLMNA | |
| SCHEMBL16985197 | 0.80 | TSHR (0.45) | PPARGMAPTLMNAHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637658-B2 | Non-fluorescent quencher compounds and biomolecular assays | APPLIED BIOSYSTEMS, LLC (US) | 2014-01-28 | — | — | US | disclosed |
| US-20130123475-A1 | Non-Fluorescent Quencher Compounds and Biomolecular Assays | Life Technologies Corporation (US) | 2013-05-16 | — | — | US | disclosed |
| US-20120220751-A1 | Non-Fluorescent Quencher Compounds and Biomolecular Assays | Life Technologies Corporation (US) | 2012-08-30 | — | — | US | disclosed |
| US-20110245462-A1 | Non-Fluorescent Quencher Compounds and Biomolecular Assays | Life Technologies Corporation (US) | 2011-10-06 | — | — | US | disclosed |
| US-20090105452-A1 | NON-FLUORESCENT QUENCHER COMPOUNDS AND BIOMOLECULAR ASSAYS | APPLERA CORPORATION (US) | 2009-04-23 | — | — | US | disclosed |
| US-20090105452-A1 | NON-FLUORESCENT QUENCHER COMPOUNDS AND BIOMOLECULAR ASSAYS | APPLERA CORPORATION (US) | 2009-04-23 | — | — | US | disclosed |
| US-20050164225-A1 | Non-fluorescent quencher compounds and biomolecular assays | APPLIED BIOSYSTEMS, LLC | 2005-07-28 | — | — | US | disclosed |
| US-20040005607-A1 | Non-fluorescent quencher compounds and biomolecular assays | APPLIED BIOSYSTEMS, LLC | 2004-01-08 | — | — | US | disclosed |
| US-20030082547-A1 | Non-fluorescent quencher compounds and biomolecular assays | APPLIED BIOSYSTEMS, LLC | 2003-05-01 | — | — | US | disclosed |
| WO-2003019145-A2 | NON-FLUORESCENT QUENCHER COMPOUNDS AND BIOMOLECULAR ASSAYS | APPLERA CORPORATION (US) | 2003-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050164225-A1 | Non-fluorescent quencher compounds and biomolecular assays | DNTT, PNP, NT5C2 | MTNR1A 2408/4885MTNR1B 3182/4885PPARG 2036/4885 |
| US-20130123475-A1 | Non-Fluorescent Quencher Compounds and Biomolecular Assays | DNTT, PNP, NT5C2 | MTNR1A 2311/4885MTNR1B 3159/4885PPARG 2076/4885 |
| US-20030082547-A1 | Non-fluorescent quencher compounds and biomolecular assays | DNTT, PNP, NT5C2 | MTNR1A 2052/4885MTNR1B 2930/4885PPARG 2233/4885 |
| US-20090105452-A1 | NON-FLUORESCENT QUENCHER COMPOUNDS AND BIOMOLECULAR ASSAYS | DNTT, PNP, NT5C2 | MTNR1A 2311/4885MTNR1B 3159/4885PPARG 2076/4885 |
| US-20040005607-A1 | Non-fluorescent quencher compounds and biomolecular assays | DNTT, PNP, NT5C2 | MTNR1A 2052/4885MTNR1B 2930/4885PPARG 2233/4885 |
| US-20110245462-A1 | Non-Fluorescent Quencher Compounds and Biomolecular Assays | DNTT, PNP, NT5C2 | MTNR1A 2311/4885MTNR1B 3159/4885PPARG 2076/4885 |
| US-20120220751-A1 | Non-Fluorescent Quencher Compounds and Biomolecular Assays | DNTT, PNP, NT5C2 | MTNR1A 2311/4885MTNR1B 3159/4885PPARG 2076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.