Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.72 |
| ▸ | ESR1 | P03372 | 1/20 | 0.72 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.72 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.72 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.68 |
| ▸ | CBS | P35520 | 1/20 | 0.68 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.68 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.68 |
| ▸ | PARP1 | P09874 | 11/20 | 0.62 |
| ▸ | PARP2 | Q9UGN5 | 11/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.60 |
| ▸ | APP | P05067 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19353997 | 0.87 | PARP1 (0.65) | PDE5AESR1PDE4DESR2PARP1 | |
| SCHEMBL1231403 | 0.84 | PDE4D (1.00) | PDE5AESR1PDE4DESR2PTPN1 | |
| SCHEMBL29808504 | 0.84 | PDE4D (1.00) | PDE5AESR1PDE4DESR2PTPN1 | |
| SCHEMBL3173991 | 0.82 | PDE5A (0.62) | PDE5AESR1PDE4DESR2PTPN1 | |
| SCHEMBL14066713 | 0.82 | CBS (0.74) | PDE5AESR1PDE4DESR2PTPN1 | |
| SCHEMBL476215 | 0.81 | CBS (0.78) | PDE5AESR1PDE4DESR2PTPN1 | |
| Cupressuflavone SCHEMBL505213 | 0.81 | CBS (1.00) | PDE5AESR1PDE4DESR2PTPN1 | |
| Cupressuflavone SCHEMBL31670258 | 0.81 | CBS (1.00) | PDE5AESR1PDE4DESR2PTPN1 | |
| SCHEMBL28986431 | 0.81 | CBS (0.78) | PDE5AESR1PDE4DESR2PTPN1 | |
| SCHEMBL29435853 | 0.81 | CBS (0.78) | PDE5AESR1PDE4DESR2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110135774-A1 | Process for Preparing a Plant Extract of Passiflora Alata and Use of Said Extract in Cosmetic and Pharmaceutical Compositions | UNIVERSIDADE FEDERAL DE SANTA CATARINA (BR) | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110135774-A1 | Process for Preparing a Plant Extract of Passiflora Alata and Use of Said Extract in Cosmetic and Pharmaceutical Compositions | CUTA, PGA5, APRT | PDE5A 368/4885ESR1 4393/4885PDE4D 1309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.