Cupressuflavone

Cupressuflavone

SCHEMBL505213

O=c1cc(-c2ccc(O)cc2)oc2c(-c3c(O)cc(O)c4c(=O)cc(-c5ccc(O)cc5)oc34)c(O)cc(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CBS P35520 2/20 1.00
PTPN1 P18031 2/20 1.00
CDK5 Q00535 2/20 1.00
CDK5R1 Q15078 2/20 1.00
MAPT P10636 4/20 0.71
PKM P14618 4/20 0.71
KDM4E B2RXH2 3/20 0.71
APEX1 P27695 3/20 0.71
CYP3A4 P08684 3/20 0.71
POLB P06746 2/20 0.71
RECQL P46063 2/20 0.71
BLM P54132 2/20 0.71
MCL1 Q07820 2/20 0.71
MIF P14174 1/20 0.71
APP P05067 6/20 0.71
PARP1 P09874 4/20 0.67
PARP2 Q9UGN5 3/20 0.67
KMT2A Q03164 4/20 0.63
TDP1 Q9NUW8 2/20 0.63
INPPL1 O15357 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cupressuflavone SCHEMBL31670258 1.00 CBS (1.00) CBSPTPN1CDK5CDK5R1MAPT
Cupressuflavone SCHEMBL4650575 0.98 CBS (0.97) CBSPTPN1CDK5CDK5R1MAPT
Agathisflavone SCHEMBL30637380 0.89 CBS (1.00) CBSPTPN1CDK5CDK5R1MAPT
Agathisflavone SCHEMBL616142 0.89 CBS (1.00) CBSPTPN1CDK5CDK5R1MAPT
SCHEMBL29435853 0.88 CBS (0.78) CBSPTPN1CDK5CDK5R1MAPT
SCHEMBL28986431 0.88 CBS (0.78) CBSPTPN1CDK5CDK5R1MAPT
SCHEMBL476215 0.88 CBS (0.78) CBSPTPN1CDK5CDK5R1MAPT
SCHEMBL14066713 0.85 CBS (0.74) CBSPTPN1CDK5CDK5R1MAPT
SCHEMBL15899618 0.84 APP (0.77) CBSPTPN1CDK5CDK5R1MAPT
SCHEMBL29574181 0.84 PTPN1 (1.00) CBSPTPN1CDK5CDK5R1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4698662-A2 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES AskBio Inc. (US) 2026-02-25 EP claimed
US-20250262233-A1 COMPOSITION SpecNova LLC (US) 2025-08-21 US claimed
EP-2603098-B1 METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER FIRMENICH INCORPORATED (US) 2025-08-06 EP claimed
WO-2024220449-A9 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES AskBio Inc. (US) 2025-04-03 WO claimed
WO-2024220449-A2 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES ASKLEPIOS BIOPHARMACEUTICAL, INC. (US) 2024-10-24 WO claimed
US-20230089704-A1 NOVEL COMPOSITION SpecNova LLC (US) 2023-03-23 US claimed
US-10244779-B2 Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer SENOMYX, INC. (US) 2019-04-02 US claimed
EP-2544554-B1 METHOD FOR STABILIZING WATER INSOLUBLE BIOACTIVE COMPOUND AQUEOUS DISPERSIONS STOKELY VAN CAMP INC (US) 2016-11-30 EP claimed
US-20150245642-A1 METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER FIRMENICH INCORPORATED 2015-09-03 US claimed
US-9000054-B2 Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer SENOMYX, INC. (US) 2015-04-07 US claimed
US-8420141-B2 Food coloring PEPSICO, INC. (US) 2013-04-16 US claimed
EP-2544554-A1 METHOD FOR STABILIZING WATER INSOLUBLE BIOACTIVE COMPOUND AQUEOUS DISPERSIONS Stokely-Van Camp, Inc. (US) 2013-01-16 EP claimed
WO-2012021837-A2 METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER SENOMYX, INC. (US) 2012-02-16 WO claimed
US-20120041078-A1 METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER SENOMYX, INC. (US) 2012-02-16 US claimed
US-20110223256-A1 Method For Stabilizing Flavonoid Aqueous Dispersion STOKELY-VAN CAMP, INC. (US) 2011-09-15 US claimed
WO-2011112386-A1 METHOD FOR STABILIZING WATER INSOLUBLE BIOACTIVE COMPOUND AQUEOUS DISPERSIONS STOKELY-VAN CAMP, INC. (US) 2011-09-15 WO claimed
US-7767238-B2 Beverage composition and method of preventing degradation of vitamins in beverages PEPSICO, INC. (US) 2010-08-03 US claimed
US-20070110851-A1 Beverage composition and method of preventing degradation of vitamins in beverages PEPSICO, INC. 2007-05-17 US claimed
EP-1782701-A1 Beverage composition and method of preventing degradation of vitamins in beverages PepsiCo, Inc. (US) 2007-05-09 EP claimed
US-20040091589-A1 Prevention of synthetic color fading in beverages using botanically derived color stabilizers PEPSICO, INC. 2004-05-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10244779-B2 Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer TFEB, TREH, SLC2A8 CBS 2043/4885PTPN1 3807/4885CDK5 1550/4885
US-20120041078-A1 METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER TFEB, TREH, SLC2A8 CBS 2043/4885PTPN1 3807/4885CDK5 1550/4885
US-20150245642-A1 METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER TFEB, TREH, SLC2A8 CBS 2043/4885PTPN1 3807/4885CDK5 1550/4885
US-20230089704-A1 NOVEL COMPOSITION NCSTN, PRSS12, DSTN CBS 902/4885PTPN1 3535/4885CDK5 2488/4885
US-20250262233-A1 COMPOSITION GNG2, DSTN, PRSS12 CBS 903/4885PTPN1 2546/4885CDK5 2896/4885
US-20110223256-A1 Method For Stabilizing Flavonoid Aqueous Dispersion MLN, NSF, CEL CBS 4182/4885PTPN1 3268/4885CDK5 103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.