Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.36 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12551963 | 0.93 | PRKCA (0.39) | PRKCAAKT1PTK2PAX8P4HB | |
| SCHEMBL12551965 | 0.91 | PRKCA (0.37) | PRKCAAKT1PTK2PAX8P4HB | |
| SCHEMBL12551969 | 0.89 | PRKCA (0.36) | PRKCAAKT1PTK2PAX8P4HB | |
| SCHEMBL12551962 | 0.88 | LMNA (0.38) | PRKCAAKT1PTK2PAX8P4HB | |
| SCHEMBL12551974 | 0.85 | LMNA (0.35) | PRKCAAKT1PTK2PAX8P4HB | |
| SCHEMBL12551983 | 0.83 | LGALS9 (0.33) | PRKCAAKT1PTK2PAX8P4HB | |
| SCHEMBL12606380 | 0.83 | PRKCA (0.49) | PRKCAAKT1PTK2PAX8P4HB | |
| SCHEMBL12606374 | 0.83 | PRKCA (0.49) | PRKCAAKT1PTK2PAX8P4HB | |
| SCHEMBL12606360 | 0.80 | PRKCA (0.49) | PRKCAAKT1PTK2PAX8P4HB | |
| SCHEMBL14478749 | 0.76 | LMNA (0.36) | PRKCAAKT1PTK2PAX8P4HB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318696-B2 | Polysaccharides with antithrombotic activity comprising at least one covalent bond with biotin or a biotin derivative | SANOFI (FR) | 2012-11-27 | — | — | US | disclosed |
| US-20110144042-A1 | Novel Polysaccharides with Antithrombotic Activity Comprising at Least One Covalent Bond with Biotin or a Biotin Derivative | SANOFI-AVENTIS (FR) | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144042-A1 | Novel Polysaccharides with Antithrombotic Activity Comprising at Least One Covalent Bond with Biotin or a Biotin Derivative | SERPINC1, SELP, FGB | PRKCA 4482/4885AKT1 4770/4885PTK2 1329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.