SCHEMBL1255640

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1256952	0.97	ADORA2A (0.62)	ADORA2AADORA1ADORA3
	SCHEMBL1254336	0.90	ADORA2A (0.66)	ADORA2AADORA1ADORA3MEN1NPC1
	SCHEMBL1254381	0.90	ADORA3 (0.63)	ADORA2AADORA1ADORA3MAPT
	SCHEMBL1254093	0.90	ADORA1 (0.63)	ADORA2AADORA1ADORA3KDM4ESMN1; SMN2
	SCHEMBL1255219	0.90	ADORA1 (0.57)	ADORA2AADORA1ADORA3NPC1KMT2A
	SCHEMBL1255351	0.90	L3MBTL1 (0.54)	ADORA2AADORA1ADORA3MEN1NPC1
	SCHEMBL1256360	0.90	ADORA2A (0.65)	ADORA2AADORA1ADORA3
	SCHEMBL1255528	0.89	L3MBTL1 (0.60)	ADORA2AADORA1ADORA3NPC1RAB9A
	SCHEMBL1256755	0.89	ADORA1 (0.64)	ADORA2AADORA1ADORA3NPC1ALDH1A1
	SCHEMBL1254509	0.88	ADORA2A (0.53)	ADORA2AADORA1ADORA3MEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.