SCHEMBL12557643

SCHEMBL12557643

CC(C)C1=CC2=C(C(=O)C1=O)[C@@]1(OC=O)CCCC(C)(C)[C@@H]1CC2

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ FDPS P14324 14/20 0.45
▸ GGPS1 O95749 8/20 0.45
▸ EP300 Q09472 1/20 0.37
▸ TP53 P04637 2/20 0.34
▸ CYP3A4 P08684 2/20 0.34
▸ HSP90AA1 P07900 1/20 0.34
▸ KDM4E B2RXH2 1/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ USP2 O75604 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ CES2 O00748 1/20 0.33
▸ CES1 P23141 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29574656 0.81 FDPS (0.50) FDPSGGPS1EP300TP53CYP3A4
SCHEMBL13197140 0.76 FDPS (0.53) FDPSGGPS1EP300TP53CYP3A4
SCHEMBL13201767 0.76 FDPS (0.53) FDPSGGPS1EP300TP53CYP3A4
SCHEMBL15732245 0.68 EP300 (0.46) FDPSGGPS1EP300TP53CYP3A4
SCHEMBL12557647 0.67 FDPS (0.63) FDPSGGPS1TP53CYP3A4KDM4E
SCHEMBL19792842 0.67 FDPS (0.63) FDPSGGPS1TP53CYP3A4KDM4E
SCHEMBL22862035 0.65 FDPS (0.39) FDPSGGPS1EP300CES2CES1
SCHEMBL9359973 0.62 CYP3A4 (0.50) FDPSGGPS1EP300TP53CYP3A4
SCHEMBL18290369 0.62 EP300 (0.56) FDPSGGPS1EP300CES2CES1
SCHEMBL8855131 0.57 KARS1 (0.51) EP300TP53CYP3A4MEN1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8299275-B2 Process for producing carnosol from carnosic acid using hydrogen peroxide or peracids DSM IP ASSETS B.V. (NL) 2012-10-30 — — US disclosed
US-20110144357-A1 PROCESS FOR PRODUCING CARNOSOL FROM CARNOSIC ACID USING HYDROGEN PEROXIDE OR PERACIDS DSM IP ASSETS B.V. (NL) 2011-06-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110144357-A1 PROCESS FOR PRODUCING CARNOSOL FROM CARNOSIC ACID USING HYDROGEN PEROXIDE OR PERACIDS FECH, CROCC, CAT FDPS 77/4885GGPS1 672/4885EP300 1963/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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