SCHEMBL1256101

SCHEMBL1256101

c1ccc(-c2ccccc2C2OCCO2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 3/20 0.41
ADRA2B P18089 2/20 0.41
ADRA2C P18825 2/20 0.41
BRD4 O60885 1/20 0.40
CHRNB2 P17787 1/20 0.39
CHRNA4 P43681 1/20 0.39
USP30 Q70CQ3 1/20 0.38
CYP11B2 P19099 3/20 0.37
ADRA1D P25100 1/20 0.37
ADRA1A P35348 1/20 0.37
ALDH1A1 P00352 3/20 0.37
HSD17B10 Q99714 2/20 0.37
HPGD P15428 1/20 0.37
BCL2L1 Q07817 1/20 0.37
CYP2A6 P11509 1/20 0.37
MAPK1 P28482 1/20 0.37
HTR2C P28335 1/20 0.37
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17687928 0.81 HSD17B1 (0.41) ADRA2AADRA2BADRA2C
SCHEMBL5609138 0.81 PDE4B (0.36) BRD4CHRNB2CHRNA4USP30ADRA1D
SCHEMBL3727526 0.79 TSHR (0.36) ADRA2BADRA2CHTR2C
SCHEMBL17667239 0.78 ADRA2A (0.41) ADRA2AADRA2BADRA2CBRD4CHRNB2
SCHEMBL2287082 0.77 PDCD1 (0.35) MAPK1HTR2C
SCHEMBL23706387 0.77 TSHR (0.48) ADRA2AADRA2BADRA2CBRD4CHRNB2
SCHEMBL28311447 0.76 CHRNB2 (0.37) CHRNB2CHRNA4MAPK1HDAC4HDAC2
SCHEMBL8251752 0.74 KDM1A (0.47) ADRA1DADRA1AALDH1A1HTR2C
SCHEMBL13356425 0.73 ADRA2A (0.41) ADRA2AADRA2BADRA2CBRD4CHRNB2
SCHEMBL15255978 0.73 ALOX5AP (0.36) ADRA2AADRA2BADRA2CUSP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150148444-A1 PRESSURE-SENSITIVE ADHESIVES AND PROCESS FOR PREPARING THEM TESA SE (DE) 2015-05-28 US disclosed
US-8969479-B2 Pressure-sensitive adhesives and process for preparing them TESA SE (DE) 2015-03-03 US disclosed
US-8536276-B2 Pressure-sensitive adhesives and process for preparing them TESA SE (DE) 2013-09-17 US disclosed
US-8372932-B2 Pressure-senstive adhesives and process for preparing them TESA SE (DE) 2013-02-12 US disclosed
US-20110039970-A1 PRESSURE-SENSTIVE ADHESIVES AND PROCESS FOR PREPARING THEM TESA SE (DE) 2011-02-17 US disclosed
US-20100010112-A1 PRESSURE-SENSITIVE ADHESIVES AND PROCESS FOR PREPARING THEM TESA AG (DE) 2010-01-14 US disclosed
US-20100010170-A1 PRESSURE-SENSITIVE ADHESIVES AND PROCESS FOR PREPARING THEM TESA AG (DE) 2010-01-14 US disclosed
US-20060257650-A1 Pressure-sensitive adhesives and process for preparing them TESA AKTIENGESELLSCHAFT (DE) 2006-11-16 US disclosed