Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 3/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23706387 | 0.83 | TSHR (0.48) | ADRA2AADRA2BADRA2CCYP11B2BRD4 | |
| SCHEMBL1538935 | 0.79 | DRD2 (0.52) | ADRA2AADRA2BADRA2CCHRNB2CHRNA4 | |
| SCHEMBL1256101 | 0.78 | ADRA2A (0.41) | ADRA2AADRA2BADRA2CCYP11B2BRD4 | |
| SCHEMBL28759921 | 0.75 | KDM1A (0.45) | ADRA1DADRA1AHTR2BHTR2CALDH1A1 | |
| SCHEMBL16393627 | 0.74 | BRD4 (0.51) | ADRA2AADRA2BADRA2CCYP11B2BRD4 | |
| Hydrogen Sulfide SCHEMBL27539552 | 0.72 | BRD4 (0.50) | ADRA2AADRA2BADRA2CCYP11B2BRD4 | |
| Ammonia Solution, Strong SCHEMBL27714733 | 0.72 | BRD4 (0.50) | ADRA2AADRA2BADRA2CCYP11B2BRD4 | |
| SCHEMBL10789751 | 0.71 | PTGS2 (0.60) | ADRA2ACYP11B2BRD4CHRNB2CHRNA4 | |
| SCHEMBL29433489 | 0.71 | PTGS2 (0.60) | ADRA2ACYP11B2BRD4CHRNB2CHRNA4 | |
| SCHEMBL28228917 | 0.71 | PTGS2 (0.56) | ADRA2AADRA2BADRA2CCYP11B2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9685597-B2 | Curable composition for sealing optical semiconductor | DAICEL CORPORATION (JP) | 2017-06-20 | — | — | US | disclosed |
| US-20160126431-A1 | CURABLE COMPOSITION FOR SEALING OPTICAL SEMICONDUCTOR | DAICEL CORPORATION (JP) | 2016-05-05 | — | — | US | disclosed |
| EP-3006481-A1 | CURABLE COMPOSITION FOR SEALING OPTICAL SEMICONDUCTOR | Daicel Corporation (JP) | 2016-04-13 | — | — | EP | disclosed |