SCHEMBL12563136

SCHEMBL12563136

Cc1cc(CO)c2c(c1)COC(C)(C)O2

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
MAPK1 P28482 1/20 0.40
KMT2A Q03164 1/20 0.40
MAOB P27338 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28172871 0.89 ALDH1A1 (0.39) ALDH1A1MAPK1KMT2AMAOB
SCHEMBL16675618 0.84 ALDH1A1 (0.40) ALDH1A1MAPK1KMT2A
SCHEMBL1054915 0.84 ALDH1A1 (0.37) ALDH1A1MAPK1KMT2AMAOB
SCHEMBL2616010 0.83 ALDH1A1 (0.36) ALDH1A1MAPK1KMT2A
SCHEMBL28849663 0.81 ALDH1A1 (0.37) ALDH1A1MAPK1KMT2AMAOB
SCHEMBL11113228 0.79 MAOB (0.36) ALDH1A1MAPK1KMT2AMAOB
SCHEMBL12035983 0.78 FFAR4 (0.39) KMT2A
SCHEMBL17531792 0.76 KMT2A (0.38) ALDH1A1MAPK1KMT2AMAOB
SCHEMBL9518641 0.76 ALDH1A1 (0.36) ALDH1A1MAPK1KMT2AMAOB
SCHEMBL28172137 0.76 ALDH1A1 (0.36) ALDH1A1MAPK1KMT2AMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2966108-B1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS SAUDI ARAMCO TECH CO (SA) 2021-03-31 EP disclosed
US-10662211-B2 Catalysts and methods for polymer synthesis Saurdi Aramco Technologies Company (SA) 2020-05-26 US disclosed
US-20180179242-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS NOVOMER, INC. 2018-06-28 US disclosed
US-20180179242-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS NOVOMER, INC. 2018-06-28 US disclosed
US-9951096-B2 Catalysts and methods for polymer synthesis SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2018-04-24 US disclosed
US-9951096-B2 Catalysts and methods for polymer synthesis SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2018-04-24 US disclosed
US-9718901-B2 Resin composition and pattern forming method using the same FUJIFILM CORPORATION (JP) 2017-08-01 US disclosed
US-9718901-B2 Resin composition and pattern forming method using the same FUJIFILM CORPORATION (JP) 2017-08-01 US disclosed
US-20170183369-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2017-06-29 US disclosed
US-20170183369-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2017-06-29 US disclosed
US-8378134-B2 Hydroxylated contrast enhancement agents GENERAL ELECTRIC COMPANY (US) 2013-02-19 US disclosed
US-20110152497-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS NOVOMER, INC. (US) 2011-06-23 US disclosed
US-20110152497-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS NOVOMER, INC. (US) 2011-06-23 US disclosed
WO-2011039244-A1 HYDROXYLATED CONTRAST ENHANCEMENT AGENTS AND INTERMEDIATES THEREOF GENERAL ELECTRIC COMPANY (US) 2011-04-07 WO disclosed
US-20110076237-A1 Hydroxylated Contrast Enhancement Agents GENERAL ELECTRIC COMPANY (US) 2011-03-31 US disclosed
US-20110076237-A1 Hydroxylated Contrast Enhancement Agents GENERAL ELECTRIC COMPANY (US) 2011-03-31 US disclosed
US-20110077417-A1 Intermediates for Hydroxylated Contrast Enhancement Agents GENERAL ELECTRIC COMPANY (US) 2011-03-31 US disclosed
US-20110077417-A1 Intermediates for Hydroxylated Contrast Enhancement Agents GENERAL ELECTRIC COMPANY (US) 2011-03-31 US disclosed
US-20110077396-A1 INTERMEDIATES FOR HYDROXYLATED CONTRAST ENHANCEMENT AGENTS GENERAL ELECTRIC COMPANY (US) 2011-03-31 US disclosed
WO-2010022388-A2 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS NOVOMER, INC. (US) 2010-02-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662211-B2 Catalysts and methods for polymer synthesis PPOX, COASY, SOD1 ALDH1A1 2255/4885MAPK1 4309/4885KMT2A 1825/4885
US-20110077417-A1 Intermediates for Hydroxylated Contrast Enhancement Agents RXFP3, HCAR3, RXFP1 ALDH1A1 3419/4885MAPK1 2490/4885KMT2A 4210/4885
US-20110077396-A1 INTERMEDIATES FOR HYDROXYLATED CONTRAST ENHANCEMENT AGENTS C1R, HCAR3, C3AR1 ALDH1A1 4130/4885MAPK1 2722/4885KMT2A 4347/4885
US-20180179242-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS PPOX, COASY, SOD1 ALDH1A1 2255/4885MAPK1 4309/4885KMT2A 1825/4885
US-20110076237-A1 Hydroxylated Contrast Enhancement Agents C5, C1R, HAMP ALDH1A1 3854/4885MAPK1 3585/4885KMT2A 4097/4885
US-20170183369-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS PPOX, COASY, SOD1 ALDH1A1 2255/4885MAPK1 4309/4885KMT2A 1825/4885
US-20110152497-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS PPOX, COASY, SOD1 ALDH1A1 2255/4885MAPK1 4309/4885KMT2A 1825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.