Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186605 | 0.78 | KDM4E (0.47) | PIK3CDALDH1A1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL11614947 | 0.78 | PIK3CD (0.55) | PIK3CDALDH1A1KDM4EPOLBCSNK1A1 | |
| SCHEMBL12099239 | 0.77 | ALDH1A1 (0.41) | PIK3CDALDH1A1KDM4EPOLBCSNK1A1 | |
| SCHEMBL19710551 | 0.76 | PLAU (0.34) | PIK3CDALDH1A1IDO1SMN1; SMN2TSHR | |
| SCHEMBL8896795 | 0.76 | PIK3CD (0.45) | PIK3CDALDH1A1KDM4EPOLB | |
| SCHEMBL18109302 | 0.75 | PIK3CD (0.51) | PIK3CDALDH1A1KDM4EPOLBIDO1 | |
| SCHEMBL1973193 | 0.75 | ALDH1A1 (0.40) | PIK3CDALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL22905389 | 0.75 | PIK3CD (0.56) | PIK3CDALDH1A1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL12955779 | 0.75 | PIK3CD (0.51) | PIK3CDALDH1A1KDM4EPOLBIDO1 | |
| SCHEMBL855910 | 0.75 | PIK3CD (0.51) | PIK3CDALDH1A1KDM4EPOLBCSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260109676-A1 | HETEROCYCLIC COMPOUNDS AND RELATED METHODS | RECURSION PHARMACEUTICALS INC (US) | 2026-04-23 | — | — | US | disclosed |
| US-12528779-B2 | Heterocyclic compounds and related methods | RECURSION PHARMACEUTICALS, INC. (US) | 2026-01-20 | — | — | US | disclosed |
| US-20240383870-A1 | HETEROCYCLIC ALDEHYDE TRAPPING COMPOUNDS AND USES THEREOF | ALDEYRA THERAPEUTICS, INC. | 2024-11-21 | — | — | US | disclosed |
| US-20240228444-A1 | HETEROCYCLIC COMPOUNDS AND RELATED METHODS | RECURSION PHARMACEUTICALS, INC. | 2024-07-11 | — | — | US | disclosed |
| WO-2024140679-A1 | SPIROCYCLIC HPK1 ANTAGONISTS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2024-07-04 | — | — | WO | disclosed |
| EP-4362930-A1 | HETEROCYCLIC ALDEHYDE TRAPPING COMPOUNDS AND USES THEREOF | Aldeyra Therapeutics, Inc. (US) | 2024-05-08 | — | — | EP | disclosed |
| US-11919868-B2 | Heterocyclic compounds and related methods | RECURSION PHARMACEUTICALS, INC. (US) | 2024-03-05 | — | — | US | disclosed |
| CN-117580569-A | Heterocyclic aldehyde capture compounds and uses thereof | 奥尔德拉医疗公司 | 2024-02-20 | — | — | CN | disclosed |
| EP-4301746-A1 | DIAZEPINE DERIVATIVES USEFUL IN THE TREATMENT OF CLOSTRIDIUM DIFFICILE | Recursion Pharmaceuticals, Inc. (US) | 2024-01-10 | — | — | EP | disclosed |
| WO-2023278816-A1 | HETEROCYCLIC ALDEHYDE TRAPPING COMPOUNDS AND USES THEREOF | ALDEYRA THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |
| US-20080004285-A1 | PYRIDO(3,2-D)PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR MEDICAL TREATMENT | 4 AZA IP NV (BE) | 2008-01-03 | — | — | US | disclosed |
| EP-1838674-A2 | HETEROARYL SULFONAMIDES AND CCR2 | ChemoCentryx Inc (US) | 2007-10-03 | — | — | EP | disclosed |
| EP-1831217-A2 | PYRIDO(3,2-D)PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR MEDICAL TREATMENT | 4 AZA IP NV (BE) | 2007-09-12 | — | — | EP | disclosed |
| US-20070037794-A1 | 4-((5-Chloro-3-(4-methyl-3-trifluoromethylbenzenesulfonylamino)pyridin-2-yl)-oxo-)1H-pyrrolo(2,3-)pyridine;interfere with ligand (monocyte chemoatactic protein-1) for chemokine receptors (CCR2); antiinflammatory agents; immunomodulators; bactericides; viricides; fungicides | CHEMOCENTRYX, INC. | 2007-02-15 | — | — | US | disclosed |
| US-20070037794-A1 | 4-((5-Chloro-3-(4-methyl-3-trifluoromethylbenzenesulfonylamino)pyridin-2-yl)-oxo-)1H-pyrrolo(2,3-)pyridine;interfere with ligand (monocyte chemoatactic protein-1) for chemokine receptors (CCR2); antiinflammatory agents; immunomodulators; bactericides; viricides; fungicides | CHEMOCENTRYX, INC. | 2007-02-15 | — | — | US | disclosed |
| US-20070037794-A1 | 4-((5-Chloro-3-(4-methyl-3-trifluoromethylbenzenesulfonylamino)pyridin-2-yl)-oxo-)1H-pyrrolo(2,3-)pyridine;interfere with ligand (monocyte chemoatactic protein-1) for chemokine receptors (CCR2); antiinflammatory agents; immunomodulators; bactericides; viricides; fungicides | CHEMOCENTRYX, INC. | 2007-02-15 | — | — | US | disclosed |
| WO-2006135993-A1 | PYRIDO(3,2-D)PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR TREATING HEPATITIS C. | GILEAD SCIENCES, INC. (US) | 2006-12-28 | — | — | WO | disclosed |
| US-20060173019-A1 | Heteroaryl sulfonamides and CCR2 | CHEMOCENTRYX, INC. | 2006-08-03 | — | — | US | disclosed |
| WO-2006076644-A2 | HETEROARYL SULFONAMIDES AND CCR2 | CHEMOCENTRYX, INC. (US) | 2006-07-20 | — | — | WO | disclosed |
| WO-2006069805-A2 | PYRIDO(3,2-D)PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR MEDICAL TREATMENT | 4 AZA IP NV (BE) | 2006-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173019-A1 | Heteroaryl sulfonamides and CCR2 | CCR2, CXCR2, CCR1 | PIK3CD 4042/4885ALDH1A1 2327/4885KDM4E 4539/4885 |
| US-20260109676-A1 | HETEROCYCLIC COMPOUNDS AND RELATED METHODS | SLC10A1, SCN1B, HSD3B2 | PIK3CD 3869/4885ALDH1A1 1952/4885KDM4E 4539/4885 |
| US-20240228444-A1 | HETEROCYCLIC COMPOUNDS AND RELATED METHODS | CYP11B2, CYP11B1, MAPT | PIK3CD 3648/4885ALDH1A1 1053/4885KDM4E 4633/4885 |
| US-20070037794-A1 | 4-((5-Chloro-3-(4-methyl-3-trifluoromethylbenzenesulfonylamino)pyridin-2-yl)-oxo-)1H-pyrrolo(2,3-)pyridine;interfere with ligand (monocyte chemoatactic protein-1) for chemokine receptors (CCR2); antiinflammatory agents; immunomodulators; bactericides; viricides; fungicides | CCR2, CCR1, CCL2 | PIK3CD 2356/4885ALDH1A1 1867/4885KDM4E 1650/4885 |
| US-12528779-B2 | Heterocyclic compounds and related methods | SLC10A1, SCN1B, NPY5R | PIK3CD 3481/4885ALDH1A1 1639/4885KDM4E 3249/4885 |
| US-20080004285-A1 | PYRIDO(3,2-D)PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR MEDICAL TREATMENT | PNPO, TYMP, PNP | PIK3CD 835/4885ALDH1A1 1225/4885KDM4E 2789/4885 |
| US-20240383870-A1 | HETEROCYCLIC ALDEHYDE TRAPPING COMPOUNDS AND USES THEREOF | ALDH1A2, ALDH2, SSB | PIK3CD 4775/4885ALDH1A1 4/4885KDM4E 1666/4885 |
| US-11919868-B2 | Heterocyclic compounds and related methods | CYP11B2, CYP11B1, MAPT | PIK3CD 3648/4885ALDH1A1 1053/4885KDM4E 4633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.