Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isobutane SCHEMBL10336228 | 0.64 | — | — | |
| SCHEMBL12475485 | 0.63 | — | — | |
| SCHEMBL5614202 | 0.60 | — | — | |
| SCHEMBL1167455 | 0.60 | — | — | |
| SCHEMBL5613975 | 0.60 | — | — | |
| SCHEMBL8658250 | 0.59 | — | — | |
| SCHEMBL1182 | 0.59 | — | — | |
| SCHEMBL6503534 | 0.59 | TRPM8 (0.56) | TRPA1TRPM8EPHX1 | |
| SCHEMBL15799172 | 0.59 | — | — | |
| SCHEMBL30604482 | 0.58 | TRPM8 (0.62) | TRPA1TRPM8EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2931228-B1 | ETHANOL-FREE MICROEMULSION PERFUMING COMPOSITIONS. | FIRMENICH & CIE (CH) | 2018-01-31 | — | — | EP | claimed |
| US-20170267943-A1 | ETHANOL-FREE MICROEMULSION PERFUMING COMPOSITIONS | FIRMENICH SA (CH) | 2017-09-21 | — | — | US | claimed |
| US-9701924-B2 | Ethanol-free microemulsion perfuming compositions | FIRMENICH SA (CH) | 2017-07-11 | — | — | US | claimed |
| US-20150322374-A1 | ETHANOL-FREE MICROEMULSION PERFUMING COMPOSITIONS | FIRMENICH SA (CH) | 2015-11-12 | — | — | US | claimed |
| EP-2931228-A1 | ETHANOL-FREE MICROEMULSION PERFUMING COMPOSITIONS | Firmenich SA (CH) | 2015-10-21 | — | — | EP | claimed |
| WO-2014090959-A1 | ETHANOL-FREE MICROEMULSION PERFUMING COMPOSITIONS | FIRMENICH SA (CH) | 2014-06-19 | — | — | WO | claimed |
| EP-2155151-B1 | Butanone derivatives and use thereof as cooling agents | GIVAUDAN SA (CH) | 2013-07-31 | — | — | EP | claimed |
| EP-2178836-B1 | AMIDE ADDITION REACTION | GIVAUDAN SA (CH) | 2013-04-17 | — | — | EP | claimed |
| US-7880011-B2 | reacting p-menthanecarboxamide in toluene with 2-vinyl pyridine, 18-crown-6 chelating agent , potassium tert-butoxide (20% in tetrahydrofuran), heating to produce N-(2-pyridin-2-ylethyl)p-menthanecarboxamide[(1R,2S,5R)-2-isopropyl-5-methyl-N-(2-(pyridin-2-yl)ethyl)cyclohexanecarboxamide | Givandan, S.A. (CH) | 2011-02-01 | — | — | US | claimed |
| US-20100197713-A1 | BUTONE DERIVATIVES USEFUL AS COOLING AGENTS | GIVAUDAN SA (CH) | 2010-08-05 | — | — | US | claimed |
| EP-2178836-A1 | AMIDE ADDITION REACTION | Givaudan SA (CH) | 2010-04-28 | — | — | EP | claimed |
| EP-2155151-A2 | ORGANIC COMPOUNDS | Givaudan SA (CH) | 2010-02-24 | — | — | EP | claimed |
| WO-2009012609-A1 | AMIDE ADDITION REACTION | GIVAUDAN SA (CH) | 2009-01-29 | — | — | WO | claimed |
| US-20090030042-A1 | Amide Addition Reaction | GIVAUDAN, SA. (CH) | 2009-01-29 | — | — | US | claimed |
| WO-2008141469-A2 | BUTONE DERIVATIVES USEFUL AS COOLING AGENTS | GIVAUDAN SA (CH) | 2008-11-27 | — | — | WO | claimed |
| US-9976108-B2 | Ethanol-free microemulsion perfuming compositions | FIRMENICH SA (CH) | 2018-05-22 | — | — | US | disclosed |
| EP-2931228-B1 | ETHANOL-FREE MICROEMULSION PERFUMING COMPOSITIONS. | FIRMENICH & CIE (CH) | 2018-01-31 | — | — | EP | disclosed |
| WO-2009012609-A1 | AMIDE ADDITION REACTION | GIVAUDAN SA (CH) | 2009-01-29 | — | — | WO | disclosed |
| US-20090030042-A1 | Amide Addition Reaction | GIVAUDAN, SA. (CH) | 2009-01-29 | — | — | US | disclosed |
| WO-2008141469-A2 | BUTONE DERIVATIVES USEFUL AS COOLING AGENTS | GIVAUDAN SA (CH) | 2008-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197713-A1 | BUTONE DERIVATIVES USEFUL AS COOLING AGENTS | C1S, HSD3B1, DECR1 | TRPA1 1136/4885TRPM8 3493/4885EPHX1 2855/4885 |
| US-20090030042-A1 | Amide Addition Reaction | HRH2, OGDH, MDH2 | TRPA1 3736/4885TRPM8 4278/4885EPHX1 757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.