Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29483215 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HTTTSHRHPGDMAOB | |
| SCHEMBL29483214 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HTTTSHRHPGDMAOB | |
| SCHEMBL20126810 | 0.82 | ALDH1A1 (0.49) | ALDH1A1HTTTSHRHPGDMAOB | |
| SCHEMBL7195787 | 0.81 | HSD17B10 (0.61) | ALDH1A1TSHRL3MBTL1PRMT5WDR77 | |
| SCHEMBL732958 | 0.81 | TDP1 (0.52) | ALDH1A1TSHRHPGDTDP1KMT2A | |
| SCHEMBL77922 | 0.81 | ALDH1A1 (0.62) | ALDH1A1HTTTSHRHPGDMAOB | |
| SCHEMBL8818395 | 0.80 | ALDH1A1 (0.53) | ALDH1A1HTTTSHRHPGDL3MBTL1 | |
| SCHEMBL4872833 | 0.80 | ALDH1A1 (0.53) | ALDH1A1HTTTSHRHPGDL3MBTL1 | |
| Nitrophenolate SCHEMBL28467659 | 0.79 | GPR35 (0.42) | ALDH1A1L3MBTL1PRMT5WDR77TDP1 | |
| SCHEMBL8539484 | 0.77 | ALDH1A1 (0.58) | ALDH1A1HTTTSHRHPGDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110366434-B | Functionalized poly (propylene fumarate) polymers prepared by ring opening polymerization using magnesium catalysts | 阿克伦大学 | 2022-04-05 | — | — | CN | claimed |
| WO-2018144849-A1 | FUNCTIONALIZED POLY(PROPYLENE FUMARATE) POLYMERS MADE BY RING OPENING POLYMERIZATION USING MAGNESIUM CATALYSTS | THE UNIVERSITY OF AKRON (US) | 2018-08-09 | — | — | WO | claimed |
| US-11499008-B2 | Functionalized poly (propylene fumarate) polymers made by ring opening polymerization using magnesium catalysts | UNIVERSITY OF AKRON (US) | 2022-11-15 | — | — | US | disclosed |
| CN-110366434-B | Functionalized poly (propylene fumarate) polymers prepared by ring opening polymerization using magnesium catalysts | 阿克伦大学 | 2022-04-05 | — | — | CN | disclosed |
| WO-2018144849-A1 | FUNCTIONALIZED POLY(PROPYLENE FUMARATE) POLYMERS MADE BY RING OPENING POLYMERIZATION USING MAGNESIUM CATALYSTS | THE UNIVERSITY OF AKRON (US) | 2018-08-09 | — | — | WO | disclosed |
| WO-2018144849-A1 | FUNCTIONALIZED POLY(PROPYLENE FUMARATE) POLYMERS MADE BY RING OPENING POLYMERIZATION USING MAGNESIUM CATALYSTS | THE UNIVERSITY OF AKRON (US) | 2018-08-09 | — | — | WO | disclosed |
| US-9701679-B2 | Modulators of 5-HT receptors and methods of use thereof | Abb Vie Deutschland GmbH & Co. KG (DE) | 2017-07-11 | — | — | US | disclosed |
| US-20150175611-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | AbbVie Deutschland GmbH & Co. KG (DE) | 2015-06-25 | — | — | US | disclosed |
| US-8846663-B2 | Modulators of 5-HT receptors and methods of use thereof | ABBVIE INC. (US) | 2014-09-30 | — | — | US | disclosed |
| US-20130310368-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | ABBVIE INC. | 2013-11-21 | — | — | US | disclosed |
| US-8546377-B2 | Modulators of 5-HT receptors and methods of use thereof | ABBVIE INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-8518933-B2 | Modulators of 5-HT receptors and methods of use thereof | ABBVIE INC. (US) | 2013-08-27 | — | — | US | disclosed |
| US-20110130382-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2011-06-02 | — | — | US | disclosed |
| US-20100273767-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130310368-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | HTR4, HTR1A, HTR1D | ALDH1A1 1176/4885HTT 1786/4885TSHR 219/4885 |
| US-20110130382-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | HTR4, HTR1A, HTR1D | ALDH1A1 1176/4885HTT 1786/4885TSHR 219/4885 |
| US-20100273767-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | HTR4, HTR1A, HTR1D | ALDH1A1 1176/4885HTT 1786/4885TSHR 219/4885 |
| US-20150175611-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | HTR4, HTR1A, HTR1D | ALDH1A1 1176/4885HTT 1786/4885TSHR 219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.