Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CCR4 | P51679 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12552673 | 0.80 | RBP4 (0.48) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1420168 | 0.78 | KHK (0.40) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL27830611 | 0.77 | ADRB1 (0.59) | ALDH1A1KMT2AKDM4EL3MBTL1L3MBTL3 | |
| SCHEMBL31165520 | 0.76 | ADRB1 (0.57) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL12552670 | 0.75 | RBP4 (0.55) | HPGDALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL1420172 | 0.73 | KDM4E (0.49) | HPGDALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL12580779 | 0.72 | SMN1; SMN2 (0.42) | ALDH1A1KDM4ENPSR1L3MBTL1CYP2C9 | |
| SCHEMBL23593003 | 0.71 | KHK (0.52) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL27810118 | 0.71 | KDM4E (0.53) | HPGDALDH1A1KMT2AHSD17B10MAPK1 | |
| SCHEMBL23764792 | 0.70 | ALDH1A1 (0.43) | HPGDALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110144107-A1 | COMPOUNDS AND COMPOSITIONS USEFUL FOR THE TREATMENT OF MALARIA | IRM LLC (BM) | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144107-A1 | COMPOUNDS AND COMPOSITIONS USEFUL FOR THE TREATMENT OF MALARIA | G6PD, DHFR, SGMS1 | HPGD 497/4885ALDH1A1 1547/4885MAPT 1077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.