Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12807173 | 0.85 | CA1 (0.43) | CA1CA2SLC22A12XDHCYP11B1 | |
| SCHEMBL12583275 | 0.83 | GPR84 (0.51) | CYP11B1GPR84MEN1KMT2AKDM4E | |
| SCHEMBL2979510 | 0.82 | GPR84 (0.49) | CYP11B1GPR84MEN1KMT2AKDM4E | |
| SCHEMBL31275912 | 0.82 | GPR84 (0.49) | CYP11B1GPR84MEN1KMT2AKDM4E | |
| SCHEMBL12583038 | 0.80 | GPR84 (0.54) | GPR84MEN1KMT2AKDM4EALOX5 | |
| SCHEMBL13170959 | 0.79 | CA1 (0.51) | CA1CA2SLC22A12XDHCYP11B1 | |
| SCHEMBL12583223 | 0.79 | CA1 (0.45) | CA1CA2SLC22A12XDHCYP11B2 | |
| SCHEMBL12583341 | 0.78 | GPR84 (0.51) | CYP11B1CYP11B2GPR84MEN1KMT2A | |
| SCHEMBL13170953 | 0.78 | CA1 (0.50) | CA1CA2SLC22A12XDHCYP11B1 | |
| SCHEMBL13170956 | 0.78 | CA1 (0.50) | CA1CA2SLC22A12XDHCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1712549-B1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME | NAGASE & CO LTD (JP) | 2018-04-11 | — | — | EP | disclosed |
| US-8716524-B2 | Optically active quaternary ammonium salt having axial asymmetry and process for producing a-amino acid and derivative thereof with the same | NAGASE & CO., LTD (JP) | 2014-05-06 | — | — | US | disclosed |
| US-8716524-B2 | Optically active quaternary ammonium salt having axial asymmetry and process for producing a-amino acid and derivative thereof with the same | NAGASE & CO., LTD (JP) | 2014-05-06 | — | — | US | disclosed |
| US-20110152562-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING a-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME | NAGASE & CO., LTD. (JP) | 2011-06-23 | — | — | US | disclosed |
| US-20110152562-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING a-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME | NAGASE & CO., LTD. (JP) | 2011-06-23 | — | — | US | disclosed |
| US-7928224-B2 | Optically active quaternary ammonium salt having axial asymmetry and process for producing α-amino acid and derivative thereof with the same | NAGASE & CO., LTD (JP) | 2011-04-19 | — | — | US | disclosed |
| US-20070161624-A1 | Optically active quaternary ammonium salt having axial asymmetry and process for producing alpha-amino acid and derivative thereof with the same | KISHIDA CHEMICAL CO., LTD. (JP) | 2007-07-12 | — | — | US | disclosed |
| US-20070161624-A1 | Optically active quaternary ammonium salt having axial asymmetry and process for producing alpha-amino acid and derivative thereof with the same | KISHIDA CHEMICAL CO., LTD. (JP) | 2007-07-12 | — | — | US | disclosed |
| US-20070135654-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING alpha-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME | NAGASE & CO., LTD (JP) | 2007-06-14 | — | — | US | disclosed |
| US-20070135654-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING alpha-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME | NAGASE & CO., LTD (JP) | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135654-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING alpha-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME | BCAT1, BCAT2, AADAT | CA1 657/4885CA2 434/4885SLC22A12 1406/4885 |
| US-20110152562-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING a-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME | BCAT1, AADAT, BCAT2 | CA1 850/4885CA2 557/4885SLC22A12 1340/4885 |
| US-20070161624-A1 | Optically active quaternary ammonium salt having axial asymmetry and process for producing alpha-amino acid and derivative thereof with the same | BCAT1, BCAT2, AADAT | CA1 657/4885CA2 434/4885SLC22A12 1406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.