Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 11/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MPI | P34949 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31275912 | 1.00 | GPR84 (0.49) | GPR84MEN1KMT2AKDM4EHPGD | |
| SCHEMBL12583275 | 0.96 | GPR84 (0.51) | GPR84MEN1KMT2AKDM4EHPGD | |
| SCHEMBL12583038 | 0.86 | GPR84 (0.54) | GPR84MEN1KMT2AKDM4EHPGD | |
| SCHEMBL12583341 | 0.84 | GPR84 (0.51) | GPR84MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL12583315 | 0.84 | HSD17B1 (0.46) | GPR84MEN1KMT2AKDM4EHPGD | |
| SCHEMBL12583304 | 0.83 | GPR84 (0.40) | GPR84MEN1KMT2AKDM4EHPGD | |
| SCHEMBL12583036 | 0.82 | GPR84 (0.55) | GPR84MEN1KMT2AKDM4EHPGD | |
| SCHEMBL12583327 | 0.82 | KIF11 (0.41) | GPR84MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL12642229 | 0.82 | GPR84 (0.40) | GPR84MEN1KMT2AKDM4EALOX5 | |
| SCHEMBL12583286 | 0.82 | CA1 (0.43) | GPR84MEN1KMT2AKDM4EALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8716524-B2 | Optically active quaternary ammonium salt having axial asymmetry and process for producing a-amino acid and derivative thereof with the same | NAGASE & CO., LTD (JP) | 2014-05-06 | — | — | US | disclosed |
| US-20110152562-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING a-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME | NAGASE & CO., LTD. (JP) | 2011-06-23 | — | — | US | disclosed |
| US-7928224-B2 | Optically active quaternary ammonium salt having axial asymmetry and process for producing α-amino acid and derivative thereof with the same | NAGASE & CO., LTD (JP) | 2011-04-19 | — | — | US | disclosed |
| US-7781425-B2 | Guanidine compound and asymmetric reaction using the same | TAKASAGO INTERNATIONAL COPORATION (JP) | 2010-08-24 | — | — | US | disclosed |
| US-7781425-B2 | Guanidine compound and asymmetric reaction using the same | TAKASAGO INTERNATIONAL COPORATION (JP) | 2010-08-24 | — | — | US | disclosed |
| US-7781425-B2 | Guanidine compound and asymmetric reaction using the same | TAKASAGO INTERNATIONAL COPORATION (JP) | 2010-08-24 | — | — | US | disclosed |
| US-20080154036-A1 | Guanidine Compound and Asymmetric Reaction Using the Same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2008-06-26 | — | — | US | disclosed |
| US-20080154036-A1 | Guanidine Compound and Asymmetric Reaction Using the Same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2008-06-26 | — | — | US | disclosed |
| US-20080154036-A1 | Guanidine Compound and Asymmetric Reaction Using the Same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2008-06-26 | — | — | US | disclosed |
| US-20070161624-A1 | Optically active quaternary ammonium salt having axial asymmetry and process for producing alpha-amino acid and derivative thereof with the same | KISHIDA CHEMICAL CO., LTD. (JP) | 2007-07-12 | — | — | US | disclosed |
| US-20070135654-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING alpha-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME | NAGASE & CO., LTD (JP) | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135654-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING alpha-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME | BCAT1, BCAT2, AADAT | GPR84 3986/4885MEN1 684/4885KMT2A 327/4885 |
| US-20080154036-A1 | Guanidine Compound and Asymmetric Reaction Using the Same | GEMIN5, PRMT5, SMS | GPR84 1435/4885MEN1 2288/4885KMT2A 914/4885 |
| US-20110152562-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING a-AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME | BCAT1, AADAT, BCAT2 | GPR84 3913/4885MEN1 694/4885KMT2A 336/4885 |
| US-20070161624-A1 | Optically active quaternary ammonium salt having axial asymmetry and process for producing alpha-amino acid and derivative thereof with the same | BCAT1, BCAT2, AADAT | GPR84 3986/4885MEN1 684/4885KMT2A 327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.