Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 5/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 3/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | FNTA | P49354 | 2/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1259273 | 0.86 | SCN5A (0.40) | SCN5ATRPA1SCN9AFNTBSIGMAR1 | |
| SCHEMBL10664108 | 0.85 | NPC1 (0.53) | NPC1RAB9ANLRP3GAA | |
| SCHEMBL1259307 | 0.83 | MAPT (0.47) | SCN5AMAOBMAOANPC1RAB9A | |
| SCHEMBL1260302 | 0.83 | KIF11 (0.55) | MAOBNPC1RAB9ANLRP3 | |
| SCHEMBL1230313 | 0.81 | MAOA (0.43) | SCN5AMAOBMAOANPC1RAB9A | |
| SCHEMBL1261437 | 0.79 | MAP4K4 (0.51) | NPC1RAB9ANLRP3 | |
| SCHEMBL11952853 | 0.79 | MMP3 (0.51) | NPC1RAB9ANLRP3CA12CA2 | |
| SCHEMBL10670239 | 0.79 | NPC1 (0.66) | MAOBMAOANPC1RAB9ANLRP3 | |
| SCHEMBL4549454 | 0.78 | NPC1 (0.65) | NPC1RAB9ANLRP3MAPTKDM4E | |
| SCHEMBL10316090 | 0.78 | NPC1 (0.56) | MAOBNPC1RAB9ANLRP3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927729-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2015-01-06 | — | — | US | disclosed |
| US-20140135364-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2014-05-15 | — | — | US | disclosed |
| US-8674109-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2014-03-18 | — | — | US | disclosed |
| US-20120190543-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| EP-2461688-A1 | PESTICIDAL COMPOSITIONS | Dow AgroSciences LLC (US) | 2012-06-13 | — | — | EP | disclosed |
| WO-2011017513-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190543-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, AADAC | SCN5A 2452/4885TRPA1 804/4885SCN9A 2177/4885 |
| US-20140135364-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PLCG2 | SCN5A 3053/4885TRPA1 518/4885SCN9A 1109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.