SCHEMBL1260302

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10664108	0.89	NPC1 (0.53)	NPC1RAB9ANLRP3GRM5MAP4K4
	SCHEMBL1259273	0.85	SCN5A (0.40)	KIF11NPC1RAB9ANLRP3GRM5
	SCHEMBL1259308	0.83	SCN5A (0.46)	NPC1RAB9ANLRP3MAOB
	SCHEMBL11952853	0.82	MMP3 (0.51)	NPC1RAB9ANLRP3GRM5MAP4K4
	SCHEMBL10670239	0.82	NPC1 (0.66)	NPC1RAB9ANLRP3MAOBGRM5
	SCHEMBL1259287	0.82	KIF11 (0.51)	KIF11NPC1RAB9ANLRP3TLR2
	SCHEMBL2743492	0.82	KIF11 (0.51)	KIF11NPC1RAB9ANLRP3TLR2
	SCHEMBL4549454	0.81	NPC1 (0.65)	NPC1RAB9ANLRP3GRM5MAP4K4
	SCHEMBL10316090	0.81	NPC1 (0.56)	NPC1RAB9ANLRP3MAOBGRM5
	SCHEMBL17082477	0.80	NPC1 (0.44)	KIF11NPC1RAB9ANLRP3TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.