Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.56 |
| ▸ | MMP13 | P45452 | 2/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
| ▸ | MMP7 | P09237 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CSGALNACT1 | Q8TDX6 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9442663 | 1.00 | MMP2 (0.56) | MMP2MMP13MMP1MMP3MMP7 | |
| SCHEMBL11072569 | 1.00 | MMP2 (0.56) | MMP2MMP13MMP1MMP3MMP7 | |
| SCHEMBL11445040 | 0.85 | MMP2 (0.49) | MMP2MMP13MMP1MMP3MMP7 | |
| SCHEMBL11197937 | 0.85 | NR1H4 (0.50) | ALDH1A1MAPTEPHX2NPC1RAB9A | |
| SCHEMBL11197943 | 0.85 | NR1H4 (0.50) | ALDH1A1MAPTEPHX2NPC1RAB9A | |
| SCHEMBL11445004 | 0.84 | ALDH1A1 (0.49) | MMP2MMP13MMP1MMP3MMP7 | |
| SCHEMBL11198025 | 0.83 | ALDH1A1 (0.52) | MMP2MMP13MMP1MMP3MMP7 | |
| SCHEMBL11198020 | 0.83 | ALDH1A1 (0.52) | MMP2MMP13MMP1MMP3MMP7 | |
| SCHEMBL735333 | 0.83 | MMP2 (0.53) | MMP2MMP13MMP1MMP3MMP7 | |
| SCHEMBL943656 | 0.83 | MMP2 (0.53) | MMP2MMP13MMP1MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038617-B1 | DIASTEREOMERS OF AMINO ACID ESTERS, PESTICIDAL COMPOSITIONS INCLUDING THEM AND METHOD OF CONTROLLING PESTS USING THEM | ZOECON CORPORATION (US) | 1983-07-20 | — | — | EP | claimed |
| EP-0038617-A1 | Diastereomers of amino acid esters, pesticidal compositions including them and method of controlling pests using them | ZOECON CORPORATION (US) | 1981-10-28 | — | — | EP | claimed |
| US-4260633-A | INSECTICIDES, MITICIDES | ZOECON CORPORATION (US) | 1981-04-07 | — | — | US | claimed |
| US-7879863-B2 | Kallikrein inhibitors such as N-((2R)-3-methyl-2-{[4-(trifluoromethyl)phenyl]amino}butyl)-2-phenylacetamide trifluoroacetate, used for the treatment of gastrointestinal disorders, periodontal diseases, skin disorders, arthritis, hypotension, edema, respiratory system disorders and proliferative diseases | AJINOMOTO CO., INC. (JP) | 2011-02-01 | — | — | US | disclosed |
| US-20070066586-A1 | ANILINE DERIVATIVES | AJINOMOTO CO., INC. (JP) | 2007-03-22 | — | — | US | disclosed |
| EP-1736465-A1 | ANILINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2006-12-27 | — | — | EP | disclosed |
| EP-0038617-B1 | DIASTEREOMERS OF AMINO ACID ESTERS, PESTICIDAL COMPOSITIONS INCLUDING THEM AND METHOD OF CONTROLLING PESTS USING THEM | ZOECON CORPORATION (US) | 1983-07-20 | — | — | EP | disclosed |
| EP-0038617-A1 | Diastereomers of amino acid esters, pesticidal compositions including them and method of controlling pests using them | ZOECON CORPORATION (US) | 1981-10-28 | — | — | EP | disclosed |
| EP-0038617-A1 | Diastereomers of amino acid esters, pesticidal compositions including them and method of controlling pests using them | ZOECON CORPORATION (US) | 1981-10-28 | — | — | EP | disclosed |
| US-4260633-A | INSECTICIDES, MITICIDES | ZOECON CORPORATION (US) | 1981-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066586-A1 | ANILINE DERIVATIVES | SERPINB1, ACE, REN | MMP2 45/4885MMP13 187/4885MMP1 118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.