Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.32 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7781837 | 1.00 | LDHA (0.40) | LDHASRRSLC22A6TP53SMN1; SMN2 | |
| SCHEMBL787741 | 0.95 | LDHA (0.36) | LDHASRRSLC22A6TP53SMN1; SMN2 | |
| SCHEMBL17733 | 0.81 | ALDH1A1 (0.46) | LDHASRRSLC22A6MAPTALDH1A1 | |
| 3-Hydroxybutyric Acid, (+/-)- SCHEMBL16915288 | 0.81 | LDHA (0.50) | LDHASRRSLC22A6TP53SMN1; SMN2 | |
| SCHEMBL11762118 | 0.80 | LDHA (0.47) | LDHASRRSLC22A6SMN1; SMN2MAPT | |
| SCHEMBL2775806 | 0.80 | CYP2C19 (0.44) | SLC22A6TP53ALDH1A1CYP2C19TDP1 | |
| SCHEMBL5665861 | 0.79 | ALDH1A1 (0.43) | TP53ALDH1A1CYP2C19TDP1 | |
| SCHEMBL28073104 | 0.79 | ALDH1A1 (0.43) | LDHASRRSLC22A6MAPTALDH1A1 | |
| (R)-3-Hydroxybutanoate SCHEMBL1533862 | 0.77 | SLC22A6 (0.56) | SLC22A6TP53SMN1; SMN2MAPTLMNA | |
| 3-Hydroxybutyric Acid, (+/-)- SCHEMBL1881926 | 0.77 | SLC22A6 (0.56) | SLC22A6TP53SMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104789505-B | Reduction prepares the method and strain of cis 3,5 dihydroxyhexanoate compound | 苏州东和盛昌生物科技有限公司 | 2018-03-06 | — | — | CN | claimed |
| CN-104342410-B | Ketone reductase mutant and preparation method thereof | 南京朗恩生物科技有限公司 | 2017-04-19 | — | — | CN | claimed |
| CN-101528917-B | Compositions and methods for preparing stereoisomerically pure statins and synthetic intermediates thereof | CODEXIS, INC. (US) | 2015-07-29 | — | — | CN | claimed |
| CN-104789505-A | Method and strain for preparing cis-3,5-dihydroxyhexanoate compound by reduction and strain | SUZHOU DONGHESHENGCHANG BIOTECHNOLOGY CO LTD | 2015-07-22 | — | — | CN | claimed |
| CN-104342410-A | Ketone reductase mutant and preparation method thereof | NANJING LANG EN BIOLOG SCIENCE & TECHNOLOGY CO LTD | 2015-02-11 | — | — | CN | claimed |
| EP-2066788-B1 | COMPOSITIONS AND METHODS FOR PRODUCING STEREOISOMERICALLY PURE STATINS AND SYNTHETIC INTERMEDIATES THEREFOR | CODEXIS INC (US) | 2014-07-23 | — | — | EP | claimed |
| US-8617864-B2 | Polynucleotides encoding ketoreductases for producing stereoisomerically pure statins and synthetic intermediates therefor | CODEXIS, INC. (US) | 2013-12-31 | — | — | US | claimed |
| US-8273547-B2 | Engineered ketoreductases and methods for producing stereoisomerically pure statins | CODEXIS, INC. (US) | 2012-09-25 | — | — | US | claimed |
| US-20110195465-A1 | Compositions and Methods for Producing Stereoisomerically Pure Statins and Synthetic Intermediates Therefor | CODEXIS, INC. (US) | 2011-08-11 | — | — | US | claimed |
| US-7879585-B2 | Ketoreductases of Saccharomyces cerevisiae; host cells | CODEXIS, INC. (US) | 2011-02-01 | — | — | US | claimed |
| CN-101528917-A | Compositions and methods for preparing stereoisomerically pure statins and synthetic intermediates thereof | CODEXIS INC (US) | 2009-09-09 | — | — | CN | claimed |
| EP-2066788-A2 | COMPOSITIONS AND METHODS FOR PRODUCING STEREOISOMERICALLY PURE STATINS AND SYNTHETIC INTERMEDIATES THEREFOR | Codexis, Inc. (US) | 2009-06-10 | — | — | EP | claimed |
| US-20080248539-A1 | COMPOSITIONS AND METHODS FOR PRODUCING STEREOISOMERICALLY PURE STATINS AND SYNTHETIC INTERMEDIATES THEREFOR | CODEXIS, INC. (US) | 2008-10-09 | — | — | US | claimed |
| WO-2008042876-A2 | COMPOSITIONS AND METHODS FOR PRODUCING STEREOISOMERICALLY PURE STATINS AND SYNTHETIC INTERMEDIATES THEREFOR | CODEXIS, INC. (US) | 2008-04-10 | — | — | WO | claimed |
| EP-1439162-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3,5-DIHYDROXYCARBOXYLIC ACID DERIVATIVE | KANEKA CORP (JP) | 2008-03-26 | — | — | EP | claimed |
| US-6998495-B2 | Method for producing optically active 3,5-dihydroxycarboxylic acid derivative | KANEKA CORPORATION (JP) | 2006-02-14 | — | — | US | claimed |
| US-20040254392-A1 | Process for producing optically active 3,5-dihydroxycarboxylic acid derivative | KANEKA CORPORATION (JP) | 2004-12-16 | — | — | US | claimed |
| EP-1439162-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3,5-DIHYDROXYCARBOXYLIC ACID DERIVATIVE | KANEKA CORPORATION (JP) | 2004-07-21 | — | — | EP | claimed |
| US-20220025411-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF BUTADIENE | GENOMATICA INC (US) | 2022-01-27 | — | — | US | disclosed |
| US-3977884-A | ELECTROLESS PLATING, COMPLEXING AGENTS, REDUCING AGENTS | SHIPLEY COMPANY, INC. (US) | 1976-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254392-A1 | Process for producing optically active 3,5-dihydroxycarboxylic acid derivative | HAO2, GRHPR, HDHD5 | LDHA 429/4885SRR 109/4885SLC22A6 4289/4885 |
| US-20080248539-A1 | COMPOSITIONS AND METHODS FOR PRODUCING STEREOISOMERICALLY PURE STATINS AND SYNTHETIC INTERMEDIATES THEREFOR | COASY, FAR1, HMGCR | LDHA 1197/4885SRR 88/4885SLC22A6 2136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.