⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12600014 | 0.82 | HRH1 (0.43) | — | |
| SCHEMBL20366999 | 0.79 | CYP3A4 (0.35) | — | |
| SCHEMBL6182586 | 0.73 | LOXL2 (0.38) | — | |
| SCHEMBL27832092 | 0.72 | KIF11 (0.38) | — | |
| Hydrochloric Acid SCHEMBL1533248 | 0.72 | LOXL2 (0.37) | — | |
| SCHEMBL15239685 | 0.71 | CNR1 (0.42) | — | |
| SCHEMBL2785385 | 0.68 | KCNA5 (0.40) | — | |
| SCHEMBL27856751 | 0.66 | L3MBTL1 (0.37) | — | |
| SCHEMBL2889152 | 0.66 | USP2 (0.44) | — | |
| SCHEMBL15660337 | 0.64 | KIF11 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9266902-B2 | Labelling reagents having a pyridine nucleus bearing a diazomethyl function, process for synthesis of such reagents and processes for detection of biological molecules | BIOMERIEUX (FR) | 2016-02-23 | — | — | US | disclosed |
| US-9266902-B2 | Labelling reagents having a pyridine nucleus bearing a diazomethyl function, process for synthesis of such reagents and processes for detection of biological molecules | BIOMERIEUX (FR) | 2016-02-23 | — | — | US | disclosed |
| US-20110111514-A1 | LABELLING REAGENTS HAVING A PYRIDINE NUCLEUS BEARING A DIAZOMETHYL FUNCTION, PROCESS FOR SYNTHESIS OF SUCH REAGENTS AND PROCESSES FOR DETECTION OF BIOLOGICAL MOLECULES | BIOMERIEUX (FR) | 2011-05-12 | — | — | US | disclosed |
| US-20110111514-A1 | LABELLING REAGENTS HAVING A PYRIDINE NUCLEUS BEARING A DIAZOMETHYL FUNCTION, PROCESS FOR SYNTHESIS OF SUCH REAGENTS AND PROCESSES FOR DETECTION OF BIOLOGICAL MOLECULES | BIOMERIEUX (FR) | 2011-05-12 | — | — | US | disclosed |