Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 9/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | PRKX | P51817 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.32 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12600013 | 0.82 | — | — | |
| SCHEMBL6182586 | 0.81 | LOXL2 (0.38) | HRH1LOXL2KIF11CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL1533248 | 0.79 | LOXL2 (0.37) | HRH1LOXL2KIF11CYP2D6CYP2C9 | |
| SCHEMBL20366999 | 0.79 | CYP3A4 (0.35) | CYP3A4 | |
| SCHEMBL20366971 | 0.79 | UHRF1 (0.35) | LOXL2KIF11KCNH2DYRK1ACYP3A4 | |
| SCHEMBL739130 | 0.76 | SLC7A5 (0.43) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL27832092 | 0.72 | KIF11 (0.38) | KIF11 | |
| SCHEMBL7383009 | 0.72 | HRH1 (0.47) | HRH1LOXL2KIF11CYP3A4CYP2D6 | |
| SCHEMBL11808675 | 0.69 | KIF11 (0.46) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2785385 | 0.68 | KCNA5 (0.40) | KIF11CYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307369-B1 | MARKER REAGENTS WITH A PYRIDINE RING WITH A DIAZOMETHYL FUNCTION SUBSTITUENT METHODS FOR SYNTHESIS OF SAID REAGENTS AND METHODS FOR DETECTING BIOLOGICAL MOLECULES | BIOMERIEUX SA (FR) | 2018-07-11 | — | — | EP | disclosed |
| US-9266902-B2 | Labelling reagents having a pyridine nucleus bearing a diazomethyl function, process for synthesis of such reagents and processes for detection of biological molecules | BIOMERIEUX (FR) | 2016-02-23 | — | — | US | disclosed |
| US-9266902-B2 | Labelling reagents having a pyridine nucleus bearing a diazomethyl function, process for synthesis of such reagents and processes for detection of biological molecules | BIOMERIEUX (FR) | 2016-02-23 | — | — | US | disclosed |
| US-20110111514-A1 | LABELLING REAGENTS HAVING A PYRIDINE NUCLEUS BEARING A DIAZOMETHYL FUNCTION, PROCESS FOR SYNTHESIS OF SUCH REAGENTS AND PROCESSES FOR DETECTION OF BIOLOGICAL MOLECULES | BIOMERIEUX (FR) | 2011-05-12 | — | — | US | disclosed |
| US-20110111514-A1 | LABELLING REAGENTS HAVING A PYRIDINE NUCLEUS BEARING A DIAZOMETHYL FUNCTION, PROCESS FOR SYNTHESIS OF SUCH REAGENTS AND PROCESSES FOR DETECTION OF BIOLOGICAL MOLECULES | BIOMERIEUX (FR) | 2011-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110111514-A1 | LABELLING REAGENTS HAVING A PYRIDINE NUCLEUS BEARING A DIAZOMETHYL FUNCTION, PROCESS FOR SYNTHESIS OF SUCH REAGENTS AND PROCESSES FOR DETECTION OF BIOLOGICAL MOLECULES | DUT, NCL, POLRMT | HRH1 3485/4885LOXL2 4226/4885KIF11 1990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.