Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 3/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14999963 | 0.90 | AGTR2 (0.33) | KAT2BHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL15000198 | 0.81 | KAT2B (0.32) | KAT2BHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL8022909 | 0.80 | P2RX3 (0.41) | CNR2 | |
| SCHEMBL1260138 | 0.77 | PIM1 (0.39) | KAT2BHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL1260182 | 0.76 | TDP1 (0.44) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL1260137 | 0.74 | CNR2 (0.32) | HSD17B10KDM4ECNR2 | |
| Hydrochloric Acid SCHEMBL1068748 | 0.70 | STING1 (0.35) | HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL14592054 | 0.69 | PPARG (0.40) | KDM4EALDH1A1HPGDMAPT | |
| Hydrochloric Acid SCHEMBL1070045 | 0.69 | ALDH1A1 (0.38) | KDM4EALDH1A1GAA | |
| SCHEMBL14592069 | 0.68 | SLC6A2 (0.47) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110046161-A1 | HCV NS3 PROTEASE INHIBITORS | MERCK SHARP & DOHME LLC | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046161-A1 | HCV NS3 PROTEASE INHIBITORS | HAVCR2, GTF3C3, CTSC | KAT2B 3609/4885HSD17B10 506/4885KDM4E 2747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.