Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | POLR1A | O95602 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1072517 | 0.79 | ALDH1A1 (0.41) | KDM4E | |
| SCHEMBL8022909 | 0.78 | P2RX3 (0.41) | CNR2 | |
| SCHEMBL1260136 | 0.76 | ALDH1A1 (0.32) | KDM4E | |
| SCHEMBL2434897 | 0.73 | USP30 (0.38) | — | |
| SCHEMBL3305629 | 0.73 | ADRB2 (0.35) | KDM4E | |
| SCHEMBL2439748 | 0.73 | USP30 (0.47) | — | |
| SCHEMBL1260528 | 0.72 | USP30 (0.33) | PIK3CD | |
| SCHEMBL14999963 | 0.72 | AGTR2 (0.33) | CNR2KDM4EHSD17B10 | |
| SCHEMBL16107194 | 0.72 | PIK3CD (0.32) | PIK3CDKDM4E | |
| SCHEMBL3305623 | 0.72 | NCEH1 (0.40) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110046161-A1 | HCV NS3 PROTEASE INHIBITORS | MERCK SHARP & DOHME LLC | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046161-A1 | HCV NS3 PROTEASE INHIBITORS | HAVCR2, GTF3C3, CTSC | CNR2 4458/4885PIK3CD 3828/4885KDM4E 2747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.