Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | ANPEP | P15144 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18065005 | 0.83 | ALDH1A1 (0.47) | MMP2ANPEPALDH1A1ATMCYP3A4 | |
| SCHEMBL13008562 | 0.83 | ALDH1A1 (0.47) | MMP2ANPEPALDH1A1ATMCYP3A4 | |
| SCHEMBL22541603 | 0.81 | PEPD (0.43) | MMP2ANPEPALDH1A1CYP3A4MAPT | |
| SCHEMBL15961007 | 0.81 | MMP2 (0.39) | MMP2ANPEPALDH1A1CYP3A4MAPT | |
| SCHEMBL2771671 | 0.79 | SMN1; SMN2 (0.42) | MMP2ANPEPALDH1A1FKBP1ASMN1; SMN2 | |
| SCHEMBL15448202 | 0.79 | MMP2 (0.41) | MMP2ANPEPALDH1A1FKBP1ASMN1; SMN2 | |
| SCHEMBL25530199 | 0.77 | HRH3 (0.38) | MMP2ANPEPFKBP1ASMN1; SMN2 | |
| SCHEMBL25530203 | 0.77 | HRH3 (0.38) | MMP2ANPEPFKBP1ASMN1; SMN2 | |
| SCHEMBL25561243 | 0.77 | FKBP1A (0.33) | MMP2ANPEPFKBP1ASMN1; SMN2 | |
| SCHEMBL25530201 | 0.77 | HRH3 (0.38) | MMP2ANPEPFKBP1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943787-B2 | Preparation of pentafluorosulfanyl (SF5) heterocycles: pyrroles and thiophenes | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2011-05-17 | — | — | US | disclosed |
| US-7943787-B2 | Preparation of pentafluorosulfanyl (SF5) heterocycles: pyrroles and thiophenes | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2011-05-17 | — | — | US | disclosed |
| US-20110040103-A1 | PREPARATION OF PENTAFLUOROSULFANYL (SF5) HETEROCYCLES: PYRROLES AND THIOPHENES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2011-02-17 | — | — | US | disclosed |
| US-20110040103-A1 | PREPARATION OF PENTAFLUOROSULFANYL (SF5) HETEROCYCLES: PYRROLES AND THIOPHENES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2011-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110040103-A1 | PREPARATION OF PENTAFLUOROSULFANYL (SF5) HETEROCYCLES: PYRROLES AND THIOPHENES | SF3B5, SFXN3, CXCR5 | MMP2 4870/4885ANPEP 3120/4885ALDH1A1 3342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.